View in EDS

Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses.

Saved in:
Bibliographic Details
Title: Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses.
Authors: Semenov AV; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation., Baykov SV; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation. Electronic address: s.baykov@spbu.ru., Soldatova NS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation. Electronic address: soldatovans@tpu.ru., Geyl KK; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation., Shetnev AA; Pharmaceutical Technology Transfer Centre, Yaroslavl State Pedagogical University Named After K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation., Boyarskiy VP; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation., Yusubov MS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation., Bormotov NI; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Serova OA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Shishkina LN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Ovchinnikova AS; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Odnoshevsky DA; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Pyankov OV; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Borisevich SS; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation; Institute of Chemical Technology', Novosibirsk State University, 1, Pirogova str., Novosibirsk, 630090, Russian Federation., Gorohov YV; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation., Nikitin VN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation., Shcherbakov DN; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation., Yarovaya OI; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation. Electronic address: ooo@nioch.nsc.ru., Salakhutdinov NF; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation., Postnikov PS; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118124. Date of Electronic Publication: 2025 Sep 08.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40946533
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Semenov+AV%22">Semenov AV</searchLink>; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Baykov+SV%22">Baykov SV</searchLink>; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation. Electronic address: s.baykov@spbu.ru.<br /><searchLink fieldCode="AU" term="%22Soldatova+NS%22">Soldatova NS</searchLink>; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation. Electronic address: soldatovans@tpu.ru.<br /><searchLink fieldCode="AU" term="%22Geyl+KK%22">Geyl KK</searchLink>; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Shetnev+AA%22">Shetnev AA</searchLink>; Pharmaceutical Technology Transfer Centre, Yaroslavl State Pedagogical University Named After K.D. Ushinsky, 108 Respublikanskaya St., Yaroslavl, 150000, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Boyarskiy+VP%22">Boyarskiy VP</searchLink>; Institute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., Saint Petersburg, 199034, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Yusubov+MS%22">Yusubov MS</searchLink>; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Bormotov+NI%22">Bormotov NI</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Serova+OA%22">Serova OA</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Shishkina+LN%22">Shishkina LN</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Ovchinnikova+AS%22">Ovchinnikova AS</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Odnoshevsky+DA%22">Odnoshevsky DA</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Pyankov+OV%22">Pyankov OV</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Borisevich+SS%22">Borisevich SS</searchLink>; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation; Institute of Chemical Technology', Novosibirsk State University, 1, Pirogova str., Novosibirsk, 630090, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Gorohov+YV%22">Gorohov YV</searchLink>; Ufa Institute of Chemistry of the Ufa Federal Research Center, 71, October Pr., Ufa, 450074, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Nikitin+VN%22">Nikitin VN</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Shcherbakov+DN%22">Shcherbakov DN</searchLink>; State Research Center of Virology and Biotechnology VECTOR, Rospotrebnadzor, 630559, Koltsovo, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Yarovaya+OI%22">Yarovaya OI</searchLink>; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation. Electronic address: ooo@nioch.nsc.ru.<br /><searchLink fieldCode="AU" term="%22Salakhutdinov+NF%22">Salakhutdinov NF</searchLink>; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation.<br /><searchLink fieldCode="AU" term="%22Postnikov+PS%22">Postnikov PS</searchLink>; Research School of Chemistry and Applied Biomedical Sciences, Tomsk Polytechnic University, Tomsk, 634034, Russian Federation; Department of Medicinal Chemistry, N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry SB RAS, Lavrentiev Ave., 9, 630090, Novosibirsk, Russian Federation.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220420510%22">European journal of medicinal chemistry</searchLink> [Eur J Med Chem] 2025 Dec 15; Vol. 300, pp. 118124. <i>Date of Electronic Publication: </i>2025 Sep 08.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Editions+Scientifiques+Elsevier%22">Editions Scientifiques Elsevier </searchLink><i>Country of Publication: </i>France <i>NLM ID: </i>0420510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1768-3254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202235234%22">02235234 </searchLink><i>NLM ISO Abbreviation: </i>Eur J Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40946533
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ejmech.2025.118124
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 118124
    Titles:
      – TitleFull: Expanding the antiviral arsenal: N-arylated 1,2,4-oxadiazol-5(4H)-ones show high activity against orthopoxviruses.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Semenov AV
      – PersonEntity:
          Name:
            NameFull: Baykov SV
      – PersonEntity:
          Name:
            NameFull: Soldatova NS
      – PersonEntity:
          Name:
            NameFull: Geyl KK
      – PersonEntity:
          Name:
            NameFull: Shetnev AA
      – PersonEntity:
          Name:
            NameFull: Boyarskiy VP
      – PersonEntity:
          Name:
            NameFull: Yusubov MS
      – PersonEntity:
          Name:
            NameFull: Bormotov NI
      – PersonEntity:
          Name:
            NameFull: Serova OA
      – PersonEntity:
          Name:
            NameFull: Shishkina LN
      – PersonEntity:
          Name:
            NameFull: Ovchinnikova AS
      – PersonEntity:
          Name:
            NameFull: Odnoshevsky DA
      – PersonEntity:
          Name:
            NameFull: Pyankov OV
      – PersonEntity:
          Name:
            NameFull: Borisevich SS
      – PersonEntity:
          Name:
            NameFull: Gorohov YV
      – PersonEntity:
          Name:
            NameFull: Nikitin VN
      – PersonEntity:
          Name:
            NameFull: Shcherbakov DN
      – PersonEntity:
          Name:
            NameFull: Yarovaya OI
      – PersonEntity:
          Name:
            NameFull: Salakhutdinov NF
      – PersonEntity:
          Name:
            NameFull: Postnikov PS
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 12
              Text: 2025 Dec 15
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1768-3254
          Numbering:
            – Type: volume
              Value: 300
          Titles:
            – TitleFull: European journal of medicinal chemistry
              Type: main
ResultId 1