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CCHFV-M based DNA vaccine is highly immunogenic in multiple species and protects against challenge in cynomolgus macaques.

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Title: CCHFV-M based DNA vaccine is highly immunogenic in multiple species and protects against challenge in cynomolgus macaques.
Authors: Suschak JJ; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Fitzpatrick CJ; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Shoemaker CJ; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Shamblin JD; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., White LE; Veterinary Medicine Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Cline CR; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Douglas CE; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Delp KL; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Burt TLA; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Lewis KD; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Ravulapalli S; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Coyne S; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Ledesma-Feliciano C; PharmaJet, 400 Corporate Circle, Unit N, Golden, CO, 80401, USA., Wilson G; PharmaJet, 400 Corporate Circle, Unit N, Golden, CO, 80401, USA., Norris SLW; Regulated Research Administration Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Scruggs JL; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Davis I; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Ricks KM; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Stefan CP; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Olshner SP; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Zeng X; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Golden JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Hooper JW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA., Garrison AR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA. Electronic address: aura.r.garrison.civ@health.mil.
Source: Antiviral research [Antiviral Res] 2025 Nov; Vol. 243, pp. 106282. Date of Electronic Publication: 2025 Sep 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8109699 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9096 (Electronic) Linking ISSN: 01663542 NLM ISO Abbreviation: Antiviral Res Subsets: MEDLINE
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  Data: CCHFV-M based DNA vaccine is highly immunogenic in multiple species and protects against challenge in cynomolgus macaques.
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  Data: <searchLink fieldCode="AU" term="%22Suschak+JJ%22">Suschak JJ</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+CJ%22">Fitzpatrick CJ</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Shoemaker+CJ%22">Shoemaker CJ</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Shamblin+JD%22">Shamblin JD</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22White+LE%22">White LE</searchLink>; Veterinary Medicine Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Cline+CR%22">Cline CR</searchLink>; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Douglas+CE%22">Douglas CE</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Delp+KL%22">Delp KL</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Burt+TLA%22">Burt TLA</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Lewis+KD%22">Lewis KD</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Ravulapalli+S%22">Ravulapalli S</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Coyne+S%22">Coyne S</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Ledesma-Feliciano+C%22">Ledesma-Feliciano C</searchLink>; PharmaJet, 400 Corporate Circle, Unit N, Golden, CO, 80401, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+G%22">Wilson G</searchLink>; PharmaJet, 400 Corporate Circle, Unit N, Golden, CO, 80401, USA.<br /><searchLink fieldCode="AU" term="%22Norris+SLW%22">Norris SLW</searchLink>; Regulated Research Administration Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Scruggs+JL%22">Scruggs JL</searchLink>; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Davis+I%22">Davis I</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Ricks+KM%22">Ricks KM</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Stefan+CP%22">Stefan CP</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Olshner+SP%22">Olshner SP</searchLink>; Diagnostic Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Zeng+X%22">Zeng X</searchLink>; Pathology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Golden+JW%22">Golden JW</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Hooper+JW%22">Hooper JW</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA.<br /><searchLink fieldCode="AU" term="%22Garrison+AR%22">Garrison AR</searchLink>; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, Maryland, 21702, USA. Electronic address: aura.r.garrison.civ@health.mil.
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  Data: <searchLink fieldCode="JN" term="%228109699%22">Antiviral research</searchLink> [Antiviral Res] 2025 Nov; Vol. 243, pp. 106282. <i>Date of Electronic Publication: </i>2025 Sep 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8109699 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-9096 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201663542%22">01663542 </searchLink><i>NLM ISO Abbreviation: </i>Antiviral Res <i>Subsets: </i>MEDLINE
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