Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic nephropathy.

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Title: Integrative transcriptomic and machine learning analyses identify HDAC9 as a key regulator of mitochondrial dysfunction and senescence-associated inflammation in diabetic nephropathy.
Authors: Huang J; Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China., Pang D; Department of Obstetrics and Gynecology, The People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, China., Fan C; Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China., Yang G; Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China., Chen J; Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China., Chen S; Department of Urology, Guangxi Medical University Cancer Hospital, Nanning, Guangxi, China.
Source: Frontiers in immunology [Front Immunol] 2025 Aug 29; Vol. 16, pp. 1627173. Date of Electronic Publication: 2025 Aug 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1627173