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Single-vessel transcriptome map pathological landscapes and reveal NR2F2-mediated smooth muscle cell phenotype acquisition in capillary malformations.

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Title: Single-vessel transcriptome map pathological landscapes and reveal NR2F2-mediated smooth muscle cell phenotype acquisition in capillary malformations.
Authors: Nguyen V; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Mao I; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA., He S; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Castellanos I; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Azuero M; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Hochman ML; The Facial Surgery Center and the Hemangioma & Malformation Treatment Center, Charleston, South Carolina 29425, USA.; Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425 USA., Rong Y; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Pernomian L; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA., Chen EH; Division of Plastic Surgery, School of Medicine, University of South Carolina, Columbia, South Carolina 29203, USA.; Division of Plastic Surgery, Prisma Health Medical Group, Columbia, South Carolina 29203, USA., Friedman HI; Division of Plastic Surgery, School of Medicine, University of South Carolina, Columbia, South Carolina 29203, USA.; Division of Plastic Surgery, Prisma Health Medical Group, Columbia, South Carolina 29203, USA., Chen YH; Department of Biochemistry, University of South Carolina, Columbia, South Carolina 29208, USA., Lu Q; Department of Biochemistry, University of South Carolina, Columbia, South Carolina 29208, USA., Fan D; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA., Wenceslau CF; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA., Chen DB; Department of Obstetrics and Gynecology, University of California, Irvine, Irvine, California 92617, USA., Nelson JS; Departments of Surgery and Biomedical Engineering, Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California 92617, USA., Jegga AG; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Biomedical Informatics, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA., Wang Y; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA.; Division of Biomedical Informatics, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA., Tan W; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Sep 17. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-vessel transcriptome map pathological landscapes and reveal NR2F2-mediated smooth muscle cell phenotype acquisition in capillary malformations.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+V%22">Nguyen V</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Mao+I%22">Mao I</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA.<br /><searchLink fieldCode="AU" term="%22He+S%22">He S</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Castellanos+I%22">Castellanos I</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Azuero+M%22">Azuero M</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Hochman+ML%22">Hochman ML</searchLink>; The Facial Surgery Center and the Hemangioma & Malformation Treatment Center, Charleston, South Carolina 29425, USA.; Department of Otolaryngology - Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425 USA.<br /><searchLink fieldCode="AU" term="%22Rong+Y%22">Rong Y</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Pernomian+L%22">Pernomian L</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.<br /><searchLink fieldCode="AU" term="%22Chen+EH%22">Chen EH</searchLink>; Division of Plastic Surgery, School of Medicine, University of South Carolina, Columbia, South Carolina 29203, USA.; Division of Plastic Surgery, Prisma Health Medical Group, Columbia, South Carolina 29203, USA.<br /><searchLink fieldCode="AU" term="%22Friedman+HI%22">Friedman HI</searchLink>; Division of Plastic Surgery, School of Medicine, University of South Carolina, Columbia, South Carolina 29203, USA.; Division of Plastic Surgery, Prisma Health Medical Group, Columbia, South Carolina 29203, USA.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Department of Biochemistry, University of South Carolina, Columbia, South Carolina 29208, USA.<br /><searchLink fieldCode="AU" term="%22Lu+Q%22">Lu Q</searchLink>; Department of Biochemistry, University of South Carolina, Columbia, South Carolina 29208, USA.<br /><searchLink fieldCode="AU" term="%22Fan+D%22">Fan D</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA.<br /><searchLink fieldCode="AU" term="%22Wenceslau+CF%22">Wenceslau CF</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA.<br /><searchLink fieldCode="AU" term="%22Chen+DB%22">Chen DB</searchLink>; Department of Obstetrics and Gynecology, University of California, Irvine, Irvine, California 92617, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+JS%22">Nelson JS</searchLink>; Departments of Surgery and Biomedical Engineering, Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California 92617, USA.<br /><searchLink fieldCode="AU" term="%22Jegga+AG%22">Jegga AG</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Biomedical Informatics, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.; Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA.; Division of Biomedical Informatics, Cincinnati Children Hospital Medical Center, Cincinnati, Ohio 45229, USA.<br /><searchLink fieldCode="AU" term="%22Tan+W%22">Tan W</searchLink>; Department of Cell Biology and Anatomy, School of Medicine, University of South Carolina, Columbia, South Carolina 29209, USA.; Department of Biomedical Engineering, College of Engineering and Computing, University of South Carolina, Columbia, South Carolina 29208, USA.
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