Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1.

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Title: Cranberry improves metabolic syndrome-related organ dysfunction in rats by modulating AMPK/SREBP1, ROCK1 and TGF-β1.
Authors: Elashmony SM; Medical Pharmacology Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Alhindi Y; Pharmacology and Toxicology Department, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Merzeban DH; Medical Physiology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt. dina.merzeban@fayoum.edu.eg., Mohammed RA; Medical Physiology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt., Elsayed AM; Histology and Cell Biology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt., Sofi MA; Histology and Cell Biology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt., Mahmoud RH; Medical Biochemistry and Molecular Biology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt., Shamardl HA; Medical Pharmacology Department, Faculty of Medicine, Fayoum University, Fayoum, 19052, Egypt., Shaker DE; Medical Pharmacology Department, Faculty of Medicine, Fayoum University, Fayoum, 19052, Egypt.
Source: Scientific reports [Sci Rep] 2025 Sep 15; Vol. 15 (1), pp. 32554. Date of Electronic Publication: 2025 Sep 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-16925-2