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HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function.

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Title: HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function.
Authors: Tripathi SK; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Grimm A; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Dahl NP; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Honaker Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Knebusch P; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Chen Y; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Cook PJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA., Rawlings DJ; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.; Department of Immunology, University of Washington, Seattle, WA 98109, USA.
Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Aug 14; Vol. 33 (3), pp. 101561. Date of Electronic Publication: 2025 Aug 14 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: HLA-A2 CAR/IL-2-CISC engineered Treg display robust in vitro and in vivo antigen-specific regulatory function.
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  Data: <searchLink fieldCode="AU" term="%22Tripathi+SK%22">Tripathi SK</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Grimm+A%22">Grimm A</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Dahl+NP%22">Dahl NP</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Honaker+Y%22">Honaker Y</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Knebusch+P%22">Knebusch P</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Cook+PJ%22">Cook PJ</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.<br /><searchLink fieldCode="AU" term="%22Rawlings+DJ%22">Rawlings DJ</searchLink>; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, 1920 Terry Avenue, Seattle, WA 98101, USA.; Department of Pediatrics, University of Washington, Seattle, WA 98105, USA.; Department of Immunology, University of Washington, Seattle, WA 98109, USA.
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  Data: <searchLink fieldCode="JN" term="%22101624857%22">Molecular therapy. Methods & clinical development</searchLink> [Mol Ther Methods Clin Dev] 2025 Aug 14; Vol. 33 (3), pp. 101561. <i>Date of Electronic Publication: </i>2025 Aug 14 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101624857 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2329-0501 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223290501%22">23290501 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Methods Clin Dev <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.omtm.2025.101561
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        Text: English
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              Text: 2025 Aug 14
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