Primed Extracellular Vesicles as a Nanotherapeutic Strategy to Enhance Granulosa Cell Function in a Model of Premature Ovarian Insufficiency and Hormonal Decline.

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Title: Primed Extracellular Vesicles as a Nanotherapeutic Strategy to Enhance Granulosa Cell Function in a Model of Premature Ovarian Insufficiency and Hormonal Decline.
Authors: Shieh JS; Department of Periodontology, School of Dentistry, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan., Chin YT; Department of Periodontology, School of Dentistry, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan., Guo JJ; Department of Orthopedics and Sports Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.; MOE China-Europe Sports Medicine Belt and Road Joint Laboratory, Soochow University, Suzhou, Jiangsu, People's Republic of China., Chiu HC; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan., Cheng HR; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan., Hsu HH; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan., Huang CY; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Division of Obstetrics and Gynecology, Tri-Service General Hospital Penghu Branch, National Defense Medical University, Penghu, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical University, Taipei City, Taiwan., Chen YH; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Division of Obstetrics and Gynecology, Tri-Service General Hospital Penghu Branch, National Defense Medical University, Penghu, Taiwan., Hsieh YY; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei City, Taiwan., Chang FW; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Taipei City Hospital, Taipei, Taiwan.
Source: International journal of nanomedicine [Int J Nanomedicine] 2025 Sep 11; Vol. 20, pp. 11099-11117. Date of Electronic Publication: 2025 Sep 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Shieh+JS%22">Shieh JS</searchLink>; Department of Periodontology, School of Dentistry, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chin+YT%22">Chin YT</searchLink>; Department of Periodontology, School of Dentistry, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Guo+JJ%22">Guo JJ</searchLink>; Department of Orthopedics and Sports Medicine, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, People's Republic of China.; MOE China-Europe Sports Medicine Belt and Road Joint Laboratory, Soochow University, Suzhou, Jiangsu, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chiu+HC%22">Chiu HC</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Cheng+HR%22">Cheng HR</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+HH%22">Hsu HH</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+CY%22">Huang CY</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Division of Obstetrics and Gynecology, Tri-Service General Hospital Penghu Branch, National Defense Medical University, Penghu, Taiwan.; Graduate Institute of Medical Sciences, National Defense Medical University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YH%22">Chen YH</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Division of Obstetrics and Gynecology, Tri-Service General Hospital Penghu Branch, National Defense Medical University, Penghu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+YY%22">Hsieh YY</searchLink>; Department and Graduate Institute of Pharmacology, College of Medicine, National Taiwan University, Taipei City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+FW%22">Chang FW</searchLink>; Department of Obstetrics and Gynecology, Tri-Service General Hospital and National Defense Medical University, Taipei City, Taiwan.; Department of Obstetrics and Gynecology, Taipei City Hospital, Taipei, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101263847%22">International journal of nanomedicine</searchLink> [Int J Nanomedicine] 2025 Sep 11; Vol. 20, pp. 11099-11117. <i>Date of Electronic Publication: </i>2025 Sep 11 (<i>Print Publication: </i>2025).
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              Text: 2025 Sep 11
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