Melatonin attenuates high-fat diet- and particulate matter-induced cardiac injury: involvement of mitochondrial quality and miR-221/222 expression.

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Title: Melatonin attenuates high-fat diet- and particulate matter-induced cardiac injury: involvement of mitochondrial quality and miR-221/222 expression.
Authors: Chen YC; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan., Lee MH; Division of Neurosurgery, Department of Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan; Department of Respiratory Care, Chang Gung University of Science and Technology, Chiayi, Taiwan., Fu SJ; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan., Lee CW; Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Puzi City, Chiayi County, Taiwan; Department of Nursing, Division of Basic Medical Sciences, and Chronic Diseases and Health Promotion Research Center, Chang Gung University of Science and Technology, Puzi City, Chiayi County, Taiwan; Research Center for Industry of Human Ecology and Research Center for Chinese Herbal Medicine, Chang Gung University of Science and Technology, Guishan District, Taoyuan City, Taiwan., Shen WC; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan., Lai TC; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan; Department of Life Sciences, College of Life Sciences, National Chung Hsing University, Taichung, Taiwan; The iEGG and Animal Biotechnology Center, National Chung Hsing University, Taichung, Taiwan., Lin SR; Department of Bioscience Technology, College of Science, Chung Yuan Christian University, Taoyuan, Taiwan; Center for Nanotechnology, Chung Yuan Christian University, Taoyuan, Taiwan., Lin SW; Department of Clinical Laboratory Sciences and Medical Biotechnology, College of Medicine, National Taiwan University, Taipei, Taiwan., Yu IS; Laboratory Animal Center, College of Medicine, National Taiwan University, Taipei, Taiwan., Chuang TY; Department of Pulmonary Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan., Tsai JS; Department of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan; Center for Complementary and Integrated Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address: jawshiun@ntu.edu.tw., Chen YL; Department of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan. Electronic address: ylchenv@ntu.edu.tw.
Source: Biochemical pharmacology [Biochem Pharmacol] 2025 Dec; Vol. 242 (Pt 3), pp. 117346. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-2968
DOI:10.1016/j.bcp.2025.117346