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Triazolo-indazole-trione-mediated disruption of Wnt/β-catenin pathway drives both autophagic and paraptotic cell deaths in colorectal cancer cells.

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Title: Triazolo-indazole-trione-mediated disruption of Wnt/β-catenin pathway drives both autophagic and paraptotic cell deaths in colorectal cancer cells.
Authors: Harsha KB; Department of Chemistry, School of Engineering, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India., Yang MH; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea., Gowda D; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India., Mohan CD; Systems Toxicology Group, FEST Division, CSIR-Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, Lucknow, Uttar Pradesh 226 001, India; Academy of Scientific and Innovative Research, Ghaziabad 201002, India., Rangappa KS; Department of Studies in Chemistry, University of Mysore, Manasagangotri, Mysore, Karnataka 570006, India. Electronic address: rangappaks@gmail.com., Ahn KS; Department of Science in Korean Medicine, Kyung Hee University, 24 Kyungheedae-ro, Dongdaemun-gu, Seoul 02447, South Korea. Electronic address: ksahn@khu.ac.kr.
Source: Pathology, research and practice [Pathol Res Pract] 2025 Nov; Vol. 275, pp. 156237. Date of Electronic Publication: 2025 Sep 17.
Publication Type: Journal Article
Journal Info: Publisher: Gustav Fischer Verlag Country of Publication: Germany NLM ID: 7806109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-0631 (Electronic) Linking ISSN: 03440338 NLM ISO Abbreviation: Pathol Res Pract Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1618-0631
DOI:10.1016/j.prp.2025.156237