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Astragaloside IV delayed the epithelial-mesenchymal transition in peritoneal fibrosis by inhibiting the activation of EGFR and PI3K-AKT pathways.

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Title: Astragaloside IV delayed the epithelial-mesenchymal transition in peritoneal fibrosis by inhibiting the activation of EGFR and PI3K-AKT pathways.
Authors: Huang Y; School of Public Health, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Chu CL; Department of Clinical Medicine and Stomatology, Hangzhou Normal University, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Qiu WH; Basic Medical Sciences, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Chen JY; Department of Clinical Medicine and Stomatology, Hangzhou Normal University, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Cao LX; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Ji SY; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Zhu B; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China., Wang GK; Department of Cardiovascular Surgery, Changhai Hospital, Naval Medical University, Shanghai 200433, China. Electronic address: dearwgk@smmu.edu.cn., Shen QQ; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Department of Nephrology, Zhejiang Provincial People's Hospital Bijie Hospital, Bijie 551700, Guizhou Province, China. Electronic address: spring198457@sina.com.
Source: Journal of integrative medicine [J Integr Med] 2025 Nov; Vol. 23 (6), pp. 694-705. Date of Electronic Publication: 2025 Sep 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101603118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2095-4964 (Print) NLM ISO Abbreviation: J Integr Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Astragaloside IV delayed the epithelial-mesenchymal transition in peritoneal fibrosis by inhibiting the activation of EGFR and PI3K-AKT pathways.
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  Data: <searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; School of Public Health, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Chu+CL%22">Chu CL</searchLink>; Department of Clinical Medicine and Stomatology, Hangzhou Normal University, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Qiu+WH%22">Qiu WH</searchLink>; Basic Medical Sciences, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+JY%22">Chen JY</searchLink>; Department of Clinical Medicine and Stomatology, Hangzhou Normal University, Hangzhou 310014, Zhejiang Province, China; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Cao+LX%22">Cao LX</searchLink>; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Ji+SY%22">Ji SY</searchLink>; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Zhu+B%22">Zhu B</searchLink>; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+GK%22">Wang GK</searchLink>; Department of Cardiovascular Surgery, Changhai Hospital, Naval Medical University, Shanghai 200433, China. Electronic address: dearwgk@smmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Shen+QQ%22">Shen QQ</searchLink>; Urology & Nephrology Center, Department of Nephrology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou 310014, Zhejiang Province, China; Department of Nephrology, Zhejiang Provincial People's Hospital Bijie Hospital, Bijie 551700, Guizhou Province, China. Electronic address: spring198457@sina.com.
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  Data: <searchLink fieldCode="JN" term="%22101603118%22">Journal of integrative medicine</searchLink> [J Integr Med] 2025 Nov; Vol. 23 (6), pp. 694-705. <i>Date of Electronic Publication: </i>2025 Sep 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101603118 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2095-4964 (Print) <i>NLM ISO Abbreviation: </i>J Integr Med <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.joim.2025.09.001
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        Text: English
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              M: 11
              Text: 2025 Nov
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