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PKR-driven ISR signaling controls synaptic translation and structural plasticity in an age-dependent manner.

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Title: PKR-driven ISR signaling controls synaptic translation and structural plasticity in an age-dependent manner.
Authors: Martínez NW; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile., Gómez F; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile., Tapia-Godoy A; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile., Roa JF; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile., Moreso-Contreras F; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile., Liu Y; Altos Labs, Inc, Bay Area Institute of Science, Redwood City, CA 94065, USA., Jara C; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile., Tapia-Rojas C; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile., Alfaro I; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Programa de Comunicación Celular en Cáncer, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina, Clínica Alemana, Universidad del Desarrollo, Santiago, 7590943, Chile., Costa-Mattioli M; Altos Labs, Inc, Bay Area Institute of Science, Redwood City, CA 94065, USA; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA., Matus S; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile. Electronic address: smatus@cienciavida.org.
Source: Neurobiology of disease [Neurobiol Dis] 2025 Nov; Vol. 216, pp. 107113. Date of Electronic Publication: 2025 Sep 19.
Publication Type: Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: PKR-driven ISR signaling controls synaptic translation and structural plasticity in an age-dependent manner.
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  Data: <searchLink fieldCode="AU" term="%22Martínez+NW%22">Martínez NW</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile.<br /><searchLink fieldCode="AU" term="%22Gómez+F%22">Gómez F</searchLink>; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile.<br /><searchLink fieldCode="AU" term="%22Tapia-Godoy+A%22">Tapia-Godoy A</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile.<br /><searchLink fieldCode="AU" term="%22Roa+JF%22">Roa JF</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile.<br /><searchLink fieldCode="AU" term="%22Moreso-Contreras+F%22">Moreso-Contreras F</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Altos Labs, Inc, Bay Area Institute of Science, Redwood City, CA 94065, USA.<br /><searchLink fieldCode="AU" term="%22Jara+C%22">Jara C</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile.<br /><searchLink fieldCode="AU" term="%22Tapia-Rojas+C%22">Tapia-Rojas C</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile.<br /><searchLink fieldCode="AU" term="%22Alfaro+I%22">Alfaro I</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Programa de Comunicación Celular en Cáncer, Instituto de Ciencias e Innovación en Medicina, Facultad de Medicina, Clínica Alemana, Universidad del Desarrollo, Santiago, 7590943, Chile.<br /><searchLink fieldCode="AU" term="%22Costa-Mattioli+M%22">Costa-Mattioli M</searchLink>; Altos Labs, Inc, Bay Area Institute of Science, Redwood City, CA 94065, USA; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Matus+S%22">Matus S</searchLink>; Centro Ciencia & Vida, Fundación Ciencia & Vida, Santiago, 8580702, Chile; Facultad de Ciencias, Universidad San Sebastián, Santiago, 8580704, Chile; Fundación Ciencia & Vida (FCV), Santiago, 8580702, Chile. Electronic address: smatus@cienciavida.org.
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  Data: <searchLink fieldCode="JN" term="%229500169%22">Neurobiology of disease</searchLink> [Neurobiol Dis] 2025 Nov; Vol. 216, pp. 107113. <i>Date of Electronic Publication: </i>2025 Sep 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9500169 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-953X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209699961%22">09699961 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Dis <i>Subsets: </i>MEDLINE
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              Text: 2025 Nov
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