Prenatal Downregulation of CB1 Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits.

Saved in:

Bibliographic Details
Title:	Prenatal Downregulation of CB1 Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits.
Authors:	Simón-Sánchez S; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., den Boon F; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., García-Rincón D; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Skrempou G; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., Paraíso-Luna J; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Aguilera A; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain., Nieto M; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain., Werkman TR; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., Guzmán M; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Chameau P; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands p.j.p.chameau@uva.nl igalvero@ucm.es., Galve-Roperh I; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain p.j.p.chameau@uva.nl igalvero@ucm.es.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.
Source:	The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Oct 15; Vol. 45 (42). Date of Electronic Publication: 2025 Oct 15.
Publication Type:	Journal Article; Research Support, Non-U.S. Gov't
Journal Info:	Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1529-2401
DOI:	10.1523/JNEUROSCI.0120-25.2025