Prenatal Downregulation of CB1 Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits.
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| Title: | Prenatal Downregulation of CB |
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| Authors: | Simón-Sánchez S; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., den Boon F; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., García-Rincón D; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Skrempou G; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., Paraíso-Luna J; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Aguilera A; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain., Nieto M; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain., Werkman TR; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands., Guzmán M; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain., Chameau P; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands p.j.p.chameau@uva.nl igalvero@ucm.es., Galve-Roperh I; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain p.j.p.chameau@uva.nl igalvero@ucm.es.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain. |
| Source: | The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Oct 15; Vol. 45 (42). Date of Electronic Publication: 2025 Oct 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40983515 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prenatal Downregulation of CB<subscript>1</subscript> Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Simón-Sánchez+S%22">Simón-Sánchez S</searchLink>; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.<br /><searchLink fieldCode="AU" term="%22den+Boon+F%22">den Boon F</searchLink>; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.<br /><searchLink fieldCode="AU" term="%22García-Rincón+D%22">García-Rincón D</searchLink>; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.<br /><searchLink fieldCode="AU" term="%22Skrempou+G%22">Skrempou G</searchLink>; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Paraíso-Luna+J%22">Paraíso-Luna J</searchLink>; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.<br /><searchLink fieldCode="AU" term="%22Aguilera+A%22">Aguilera A</searchLink>; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain.<br /><searchLink fieldCode="AU" term="%22Nieto+M%22">Nieto M</searchLink>; Department of Molecular and Cellular Biology, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas (CNB-CSIC), Madrid 28049, Spain.<br /><searchLink fieldCode="AU" term="%22Werkman+TR%22">Werkman TR</searchLink>; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands.<br /><searchLink fieldCode="AU" term="%22Guzmán+M%22">Guzmán M</searchLink>; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain.<br /><searchLink fieldCode="AU" term="%22Chameau+P%22">Chameau P</searchLink>; Cellular and Computational Neuroscience, Center for Neurosciences, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam 1090 GE, Netherlands p.j.p.chameau@uva.nl igalvero@ucm.es.<br /><searchLink fieldCode="AU" term="%22Galve-Roperh+I%22">Galve-Roperh I</searchLink>; Department of Biochemistry and Molecular Biology, School of Chemistry, and Instituto Universitario de Investigación Neuroquímica (IUIN), Complutense University, Madrid 28040, Spain p.j.p.chameau@uva.nl igalvero@ucm.es.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Madrid 28029, Spain.; Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid 28034, Spain. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228102140%22">The Journal of neuroscience : the official journal of the Society for Neuroscience</searchLink> [J Neurosci] 2025 Oct 15; Vol. 45 (42). <i>Date of Electronic Publication: </i>2025 Oct 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Society+for+Neuroscience%22">Society for Neuroscience </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8102140 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1529-2401 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202706474%22">02706474 </searchLink><i>NLM ISO Abbreviation: </i>J Neurosci <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40983515 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1523/JNEUROSCI.0120-25.2025 Languages: – Code: eng Text: English Titles: – TitleFull: Prenatal Downregulation of CB1 Cannabinoid Receptors in the Mouse Prefrontal Cortex Disrupts Cortical Lamination and Induces a Transcriptional Signature Associated with Social Interaction Deficits. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Simón-Sánchez S – PersonEntity: Name: NameFull: den Boon F – PersonEntity: Name: NameFull: García-Rincón D – PersonEntity: Name: NameFull: Skrempou G – PersonEntity: Name: NameFull: Paraíso-Luna J – PersonEntity: Name: NameFull: Aguilera A – PersonEntity: Name: NameFull: Nieto M – PersonEntity: Name: NameFull: Werkman TR – PersonEntity: Name: NameFull: Guzmán M – PersonEntity: Name: NameFull: Chameau P – PersonEntity: Name: NameFull: Galve-Roperh I IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 10 Text: 2025 Oct 15 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1529-2401 Numbering: – Type: volume Value: 45 – Type: issue Value: 42 Titles: – TitleFull: The Journal of neuroscience : the official journal of the Society for Neuroscience Type: main |
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