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Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs.

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Title: Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs.
Authors: Kee JX; Department of Chemistry, Faculty of Science, National University of Singapore, Singapore 117544, Singapore., Yau JNN; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore., Kumar Muthuramalingam RP; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore., Wang X; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore., Chng WH; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore., Lopez-Sanchez A; Laboratoire Chimie Physique et Chimie du Vivant CPCV, Département de Chimie, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 24 rue Lhomond75005 Paris, France., Tay KKW; Gleneagles Hospital, 6A Napier Road Singapore 228510, Singapore.; Mount Elizabeth Hospital, 3 Mount Elizabeth, Singapore 258500, Singapore., Deng LW; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore., Gibson D; Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel., Bertrand HC; Laboratoire Chimie Physique et Chimie du Vivant CPCV, Département de Chimie, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 24 rue Lhomond75005 Paris, France., Adriani G; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.; Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117583, Republic of Singapore.; Lee Kong Chian School of Medicine (LKC Medicine), Nanyang Technological University, Singapore 308232, Singapore., Ang WH; Department of Chemistry, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore., Pastorin G; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore.
Source: Chemical reviews [Chem Rev] 2025 Nov 12; Vol. 125 (21), pp. 10248-10341. Date of Electronic Publication: 2025 Sep 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985134R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6890 (Electronic) Linking ISSN: 00092665 NLM ISO Abbreviation: Chem Rev Subsets: MEDLINE
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  Data: Colorectal Cancer at the Crossroads: The Good, the Bad, and the Future of Platinum-Based Drugs.
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  Data: <searchLink fieldCode="AU" term="%22Kee+JX%22">Kee JX</searchLink>; Department of Chemistry, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.<br /><searchLink fieldCode="AU" term="%22Yau+JNN%22">Yau JNN</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore.<br /><searchLink fieldCode="AU" term="%22Kumar+Muthuramalingam+RP%22">Kumar Muthuramalingam RP</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.<br /><searchLink fieldCode="AU" term="%22Chng+WH%22">Chng WH</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.<br /><searchLink fieldCode="AU" term="%22Lopez-Sanchez+A%22">Lopez-Sanchez A</searchLink>; Laboratoire Chimie Physique et Chimie du Vivant CPCV, Département de Chimie, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 24 rue Lhomond75005 Paris, France.<br /><searchLink fieldCode="AU" term="%22Tay+KKW%22">Tay KKW</searchLink>; Gleneagles Hospital, 6A Napier Road Singapore 228510, Singapore.; Mount Elizabeth Hospital, 3 Mount Elizabeth, Singapore 258500, Singapore.<br /><searchLink fieldCode="AU" term="%22Deng+LW%22">Deng LW</searchLink>; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117596, Singapore.; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Gibson+D%22">Gibson D</searchLink>; Institute for Drug Research, School of Pharmacy, The Hebrew University of Jerusalem, Jerusalem, 91120, Israel.<br /><searchLink fieldCode="AU" term="%22Bertrand+HC%22">Bertrand HC</searchLink>; Laboratoire Chimie Physique et Chimie du Vivant CPCV, Département de Chimie, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 24 rue Lhomond75005 Paris, France.<br /><searchLink fieldCode="AU" term="%22Adriani+G%22">Adriani G</searchLink>; Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Singapore 138648, Singapore.; Department of Biomedical Engineering, National University of Singapore, 4 Engineering Drive 3, Singapore 117583, Republic of Singapore.; Lee Kong Chian School of Medicine (LKC Medicine), Nanyang Technological University, Singapore 308232, Singapore.<br /><searchLink fieldCode="AU" term="%22Ang+WH%22">Ang WH</searchLink>; Department of Chemistry, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore.<br /><searchLink fieldCode="AU" term="%22Pastorin+G%22">Pastorin G</searchLink>; Department of Pharmacy and Pharmaceutical Sciences, Faculty of Science, National University of Singapore, Singapore 117544, Singapore.; Integrative Sciences and Engineering Programme, NUS Graduate School, National University of Singapore, Singapore 119077, Singapore.
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