Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.

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Title: Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.
Authors: Milan M; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom., Runfola V; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Patel M; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom., Falbo L; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy., Noberini R; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Soriani C; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Rodighiero S; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Bonaldi T; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy.; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Costanzo V; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy., Pradeepa MM; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom., Scaffidi P; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom.; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.
Source: Nucleic acids research [Nucleic Acids Res] 2025 Sep 23; Vol. 53 (18).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1362-4962
DOI:10.1093/nar/gkaf916