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Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.

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Title: Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.
Authors: Milan M; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom., Runfola V; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Patel M; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom., Falbo L; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy., Noberini R; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Soriani C; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Rodighiero S; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Bonaldi T; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy.; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy., Costanzo V; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy., Pradeepa MM; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom., Scaffidi P; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom.; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.
Source: Nucleic acids research [Nucleic Acids Res] 2025 Sep 23; Vol. 53 (18).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mammalian H4K16ac regulates the spatiotemporal order of genome replication rather than gene expression.
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  Data: <searchLink fieldCode="AU" term="%22Milan+M%22">Milan M</searchLink>; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Runfola+V%22">Runfola V</searchLink>; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Patel+M%22">Patel M</searchLink>; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Falbo+L%22">Falbo L</searchLink>; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy.<br /><searchLink fieldCode="AU" term="%22Noberini+R%22">Noberini R</searchLink>; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Soriani+C%22">Soriani C</searchLink>; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Rodighiero+S%22">Rodighiero S</searchLink>; Imaging Unit, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Bonaldi+T%22">Bonaldi T</searchLink>; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy.; Nuclear Proteomics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.<br /><searchLink fieldCode="AU" term="%22Costanzo+V%22">Costanzo V</searchLink>; DNA Metabolism, IFOM-ETS, The AIRC Institute of Molecular Oncology, Milan, 20139, Italy.; Department of Oncology and Haemato-Oncology, University of Milano, Milan, 20122, Italy.<br /><searchLink fieldCode="AU" term="%22Pradeepa+MM%22">Pradeepa MM</searchLink>; Blizard Institute, Centre for Epigenetics, Faculty of Medicine and Dentistry, Queen Mary University of London, London, E1 2AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Scaffidi+P%22">Scaffidi P</searchLink>; Cancer Epigenetics Laboratory, The Francis Crick Institute, London, NW1 1AT, United Kingdom.; Cancer Epigenetics, Department of Experimental Oncology, IEO, European Institute of Oncology IRCCS, Milan, 20139, Italy.
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              Text: 2025 Sep 23
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