Clinical implications of bone marrow adiposity identified by phenome-wide association and Mendelian randomization in the UK Biobank.
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| Title: | Clinical implications of bone marrow adiposity identified by phenome-wide association and Mendelian randomization in the UK Biobank. |
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| Authors: | Xu W; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK.; Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK., Mesa-Eguiagaray I; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Morris DM; Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK., Wang C; Edinburgh Imaging, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK.; School of Mathematics and Computer Sciences, Heriot-Watt University, Edinburgh, UK., Gray CD; Edinburgh Imaging, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK., Sjöström S; Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK., Papanastasiou G; Edinburgh Imaging, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK.; Archimedes Unit, Athena Research Centre, Artemidos 1, Marousi, Greece., Badr S; Univ. Lille, CHU Lille, Marrow Adiposity and Bone Laboratory (MABlab) ULR 4490, Department of Rheumatology, Lille, France., Paccou J; Univ. Lille, CHU Lille, Marrow Adiposity and Bone Laboratory (MABlab) ULR 4490, Department of Rheumatology, Lille, France., Wang L; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK., Li X; Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China., Timmers PRHJ; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK., Timofeeva M; Medical Research Council Human Genetics Unit, Medical Research Council Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Danish Institute for Advanced Study (DIAS), Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark., Semple SI; Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK.; Edinburgh Imaging, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK., MacGillivray T; Centre for Clinical Brain Sciences, University of Edinburgh, The Queen's Medical Research Institute, Edinburgh BioQuarter, 47 Little France Crescent, Edinburgh, UK., Theodoratou E; Centre for Global Health, Usher Institute, University of Edinburgh, Edinburgh, UK. E.Theodoratou@ed.ac.uk.; Edinburgh Cancer Research Centre, Institute of Genetics and Cancer, University of Edinburgh, Edinburgh, UK. E.Theodoratou@ed.ac.uk., Cawthorn WP; Institute for Neuroscience and Cardiovascular Research, The University of Edinburgh, Edinburgh, UK. W.Cawthorn@ed.ac.uk. |
| Source: | Nature communications [Nat Commun] 2025 Sep 23; Vol. 16 (1), pp. 8332. Date of Electronic Publication: 2025 Sep 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63395-1 |
