Impaired early type I interferon responses to influenza virus infection in aged mice are associated with subsequent increased pulmonary inflammation.
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| Title: | Impaired early type I interferon responses to influenza virus infection in aged mice are associated with subsequent increased pulmonary inflammation. |
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| Authors: | Wu W; Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, 800 N. Research Pkwy, Oklahoma City, OK, 73104, USA. wenxin-wu@ouhsc.edu., Alexander JS; Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, 800 N. Research Pkwy, Oklahoma City, OK, 73104, USA., Booth JL; Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, 800 N. Research Pkwy, Oklahoma City, OK, 73104, USA., Huang C; The Lundberg-Kienlen Lung Diseases and Infection Laboratory, Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA., Liu L; The Lundberg-Kienlen Lung Diseases and Infection Laboratory, Department of Physiological Sciences, Oklahoma State University, Stillwater, OK, USA., Miller CA; Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA., Drevets DA; Infectious Diseases, Department of Medicine, University of Oklahoma Health Sciences Center, 800 Stanton L. Young Blvd, Suite 7300, Oklahoma City, OK, 73104, USA. douglas-drevets@ouhsc.edu., Metcalf JP; Pulmonary, Critical Care & Sleep Medicine, Department of Medicine, University of Oklahoma Health Sciences Center, Room 425, 800 N. Research Pkwy, Oklahoma City, OK, 73104, USA. jordan-metcalf@ouhsc.edu.; Veterans Affairs Medical Center, Oklahoma City, OK, USA. jordan-metcalf@ouhsc.edu.; Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. jordan-metcalf@ouhsc.edu. |
| Source: | GeroScience [Geroscience] 2026 Jun; Vol. 48 (3), pp. 4225-4245. Date of Electronic Publication: 2025 Sep 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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