Caspofungin paradoxical growth in Candida albicans requires stress pathway activation and promotes unstable echinocandin resistance mediated by aneuploidy.

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Title: Caspofungin paradoxical growth in Candida albicans requires stress pathway activation and promotes unstable echinocandin resistance mediated by aneuploidy.
Authors: Wei Y; Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Wang J; Department of Pharmacy, Zibo Zhoucun People's Hospital, Zibo, China., Tang N; Department of Public Health, Zibo Zhoucun People's Hospital, Zibo, China., Lin Z; Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Li W; Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, China., Xu Y; Department of Pharmacy, The 960th Hospital of PLA, Jinan, China., Guo L; Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2025 Sep 08; Vol. 15, pp. 1618815. Date of Electronic Publication: 2025 Sep 08 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2235-2988
DOI:10.3389/fcimb.2025.1618815