Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase.

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Title: Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase.
Authors: Violante S; Donald B. and Catherine C. Marron Cancer Metabolism Center, Mass Spectrometry Core, Memorial Sloan Kettering Cancer Center, New York City, NY 10065., Kyaw A; Donald B. and Catherine C. Marron Cancer Metabolism Center, Mass Spectrometry Core, Memorial Sloan Kettering Cancer Center, New York City, NY 10065., Kouatli L; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824., Paladugu K; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824., Apostolakis L; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824., Jenks M; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824., Johnson A; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI 49503., Sheldon RD; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI 49503., Whitten D; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824., Schilmiller AL; Mass Spectrometry and Metabolomics Core, Michigan State University, East Lansing, MI 48824., Visconti PE; Department of Veterinary and Animal Science, University of Massachusetts, Amherst, MA 01003., Cross JR; Donald B. and Catherine C. Marron Cancer Metabolism Center, Mass Spectrometry Core, Memorial Sloan Kettering Cancer Center, New York City, NY 10065., Levin LR; Department of Pharmacology, Weill Cornell Medicine, New York City, NY 10065., Buck J; Department of Pharmacology, Weill Cornell Medicine, New York City, NY 10065., Balbach M; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Sep 30; Vol. 122 (39), pp. e2506417122. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2506417122