Design of facilitated dissociation enables timing of cytokine signalling.

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Bibliographic Details
Title: Design of facilitated dissociation enables timing of cytokine signalling.
Authors: Broerman AJ; Institute for Protein Design, University of Washington, Seattle, WA, USA. broerman@uw.edu.; Department of Biochemistry, University of Washington, Seattle, WA, USA. broerman@uw.edu.; Department of Chemical Engineering, University of Washington, Seattle, WA, USA. broerman@uw.edu., Pollmann C; Department of Biology/Chemistry, Osnabrück University, Osnabrück, Germany.; Center for Cellular Nanoanalytics, Osnabrück University, Osnabrück, Germany., Zhao Y; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Lichtenstein MA; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Institute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany., Jackson MD; Department of Chemistry, University of Washington, Seattle, WA, USA., Tessmer MH; Department of Chemistry, University of Washington, Seattle, WA, USA., Ryu WH; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA., Ogishi M; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA., Abedi MH; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Sahtoe DD; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Allen A; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Kang A; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., De La Cruz J; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Brackenbrough E; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Sankaran B; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA., Bera AK; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Biochemistry, University of Washington, Seattle, WA, USA., Zuckerman DM; Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA., Stoll S; Department of Chemistry, University of Washington, Seattle, WA, USA., Garcia KC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA, USA.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA., Praetorius F; Institute for Protein Design, University of Washington, Seattle, WA, USA. florian.praetorius@ist.ac.at.; Department of Biochemistry, University of Washington, Seattle, WA, USA. florian.praetorius@ist.ac.at.; Institute of Science and Technology Austria, Klosterneuburg, Austria. florian.praetorius@ist.ac.at., Piehler J; Department of Biology/Chemistry, Osnabrück University, Osnabrück, Germany.; Center for Cellular Nanoanalytics, Osnabrück University, Osnabrück, Germany., Baker D; Institute for Protein Design, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Department of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. dabaker@uw.edu.
Source: Nature [Nature] 2025 Nov; Vol. 647 (8089), pp. 528-535. Date of Electronic Publication: 2025 Sep 24.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4687
DOI:10.1038/s41586-025-09549-z