Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer.
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| Title: | Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer. |
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| Authors: | Nayak A; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Nayak D; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Jia L; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Ruben EA; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Viswanadhapalli S; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA., Dos Santos Bury P; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Nassar KM; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA., Yu CH; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Tumanova AA; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Stratton CM; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Ebadi P; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Ivanov DN; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Sung P; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA., Vadlamudi RK; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA.; Audie L. Murphy Division, South Texas Veterans Health Care System, San Antonio, TX, USA., Wasmuth EV; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA., Olsen SK; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. olsens@uthscsa.edu.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA. olsens@uthscsa.edu. |
| Source: | Nature structural & molecular biology [Nat Struct Mol Biol] 2025 Dec; Vol. 32 (12), pp. 2441-2453. Date of Electronic Publication: 2025 Sep 25. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40999065 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Nayak+A%22">Nayak A</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Nayak+D%22">Nayak D</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Jia+L%22">Jia L</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ruben+EA%22">Ruben EA</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Viswanadhapalli+S%22">Viswanadhapalli S</searchLink>; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+Bury+P%22">Dos Santos Bury P</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Nassar+KM%22">Nassar KM</searchLink>; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yu+CH%22">Yu CH</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tumanova+AA%22">Tumanova AA</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Stratton+CM%22">Stratton CM</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ebadi+P%22">Ebadi P</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ivanov+DN%22">Ivanov DN</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sung+P%22">Sung P</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Vadlamudi+RK%22">Vadlamudi RK</searchLink>; Department of Obstetrics and Gynecology, University of Texas Health, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA.; Audie L. Murphy Division, South Texas Veterans Health Care System, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wasmuth+EV%22">Wasmuth EV</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Olsen+SK%22">Olsen SK</searchLink>; Department of Biochemistry and Structural Biology and Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA. olsens@uthscsa.edu.; Mays Cancer Center, University of Texas Health San Antonio, San Antonio, TX, USA. olsens@uthscsa.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101186374%22">Nature structural & molecular biology</searchLink> [Nat Struct Mol Biol] 2025 Dec; Vol. 32 (12), pp. 2441-2453. <i>Date of Electronic Publication: </i>2025 Sep 25. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. 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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40999065 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41594-025-01681-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2441 Titles: – TitleFull: Cryo-EM structures reveal the molecular mechanism of SUMO E1-E2 thioester transfer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Nayak A – PersonEntity: Name: NameFull: Nayak D – PersonEntity: Name: NameFull: Jia L – PersonEntity: Name: NameFull: Ruben EA – PersonEntity: Name: NameFull: Viswanadhapalli S – PersonEntity: Name: NameFull: Dos Santos Bury P – PersonEntity: Name: NameFull: Nassar KM – PersonEntity: Name: NameFull: Yu CH – PersonEntity: Name: NameFull: Tumanova AA – PersonEntity: Name: NameFull: Stratton CM – PersonEntity: Name: NameFull: Ebadi P – PersonEntity: Name: NameFull: Ivanov DN – PersonEntity: Name: NameFull: Sung P – PersonEntity: Name: NameFull: Vadlamudi RK – PersonEntity: Name: NameFull: Wasmuth EV – PersonEntity: Name: NameFull: Olsen SK IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2025 Dec Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1545-9985 Numbering: – Type: volume Value: 32 – Type: issue Value: 12 Titles: – TitleFull: Nature structural & molecular biology Type: main |
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