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Sepsis-induced hypocholesterolemia is linked to low cardiomyocyte membrane cholesterol and impaired catecholamine responsiveness.

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Title: Sepsis-induced hypocholesterolemia is linked to low cardiomyocyte membrane cholesterol and impaired catecholamine responsiveness.
Authors: Kleyman A; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK., Pisciotta W; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Department of Anaesthesia and Intensive Care, IRCCS-ISMETT (Istituto Mediterraneo per Trapianti e Terapie ad alta specializzazione), Palermo, Italy., Gaupp C; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Department of Internal Medicine, Spital Limmattal, Schlieren, CH-8952, Switzerland., Khaliq W; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK., Hofmaenner D; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Brealey D; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Dept of Critical Care, University College London Hospitals NHS Foundation Trust, London, UK., Pinto BB; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland., Andreis DT; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; S.C. Anaesthesia and Intensive Care, Legnano Hospital, ASST Ovest Milanese, Milan, Italy., Waugh MG; Division of Medicine, University College London, London, UK., Melis MJ; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK., Miller M; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK., Mehmetaj K; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany., Bauer M; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany., Press A; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany., Singer M; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK. m.singer@ucl.ac.uk.
Source: Critical care (London, England) [Crit Care] 2025 Sep 25; Vol. 29 (1), pp. 399. Date of Electronic Publication: 2025 Sep 25.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sepsis-induced hypocholesterolemia is linked to low cardiomyocyte membrane cholesterol and impaired catecholamine responsiveness.
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  Data: <searchLink fieldCode="AU" term="%22Kleyman+A%22">Kleyman A</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Pisciotta+W%22">Pisciotta W</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Department of Anaesthesia and Intensive Care, IRCCS-ISMETT (Istituto Mediterraneo per Trapianti e Terapie ad alta specializzazione), Palermo, Italy.<br /><searchLink fieldCode="AU" term="%22Gaupp+C%22">Gaupp C</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Department of Internal Medicine, Spital Limmattal, Schlieren, CH-8952, Switzerland.<br /><searchLink fieldCode="AU" term="%22Khaliq+W%22">Khaliq W</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Hofmaenner+D%22">Hofmaenner D</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Brealey+D%22">Brealey D</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Dept of Critical Care, University College London Hospitals NHS Foundation Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Pinto+BB%22">Pinto BB</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; Division of Anaesthesiology, Geneva University Hospitals, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Andreis+DT%22">Andreis DT</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.; S.C. Anaesthesia and Intensive Care, Legnano Hospital, ASST Ovest Milanese, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Waugh+MG%22">Waugh MG</searchLink>; Division of Medicine, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Melis+MJ%22">Melis MJ</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Miller+M%22">Miller M</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Mehmetaj+K%22">Mehmetaj K</searchLink>; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Bauer+M%22">Bauer M</searchLink>; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Press+A%22">Press A</searchLink>; Dept of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Singer+M%22">Singer M</searchLink>; Bloomsbury Institute of Intensive Care Medicine, Division of Medicine, University College London, Cruciform Building, Gower St, London, WC1E 6BT, UK. m.singer@ucl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229801902%22">Critical care (London, England)</searchLink> [Crit Care] 2025 Sep 25; Vol. 29 (1), pp. 399. <i>Date of Electronic Publication: </i>2025 Sep 25.
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