A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation.
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| Title: | A domain-swapped CaMKII conformation facilitates linker-mediated allosteric regulation. |
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| Authors: | Nguyen BV; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Chemistry-Biology Interface Training Program, University of Massachusetts, Amherst, MA, USA.; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Özden C; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Dong K; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Department of Chemistry, University of Massachusetts, Amherst, MA, USA., Koc OC; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA.; Biotechnology Training Program, University of Massachusetts, Amherst, MA, USA., Torres-Ocampo AP; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Chemistry-Biology Interface Training Program, University of Massachusetts, Amherst, MA, USA.; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Dziedzic N; Molecular and Cellular Biology Graduate Program, University of Massachusetts, Amherst, MA, USA.; Chemistry-Biology Interface Training Program, University of Massachusetts, Amherst, MA, USA.; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Flaherty D; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Huang J; Chemistry-Biology Interface Training Program, University of Massachusetts, Amherst, MA, USA.; Department of Chemistry, University of Massachusetts, Amherst, MA, USA., Sankara S; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Abromson NL; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Tomchick DR; Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA., Fissore RA; Department of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA, USA., Chen J; Department of Chemistry, University of Massachusetts, Amherst, MA, USA., Garman SC; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA., Stratton MM; Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA, USA. mstratton@umass.edu. |
| Source: | Nature communications [Nat Commun] 2025 Sep 26; Vol. 16 (1), pp. 8461. Date of Electronic Publication: 2025 Sep 26. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63249-w |
