View in EDS

Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.

Saved in:
Bibliographic Details
Title: Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.
Authors: Stanley-Smith AE; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Coates N; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Fox JC; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Delfino F; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Degrado S; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States., Kunz A; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Mao S; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Zhao F; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Garforth B; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Hold A; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Hong H; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Kendall J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Lane J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Meï C; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Murphy A; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Pogwizd J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Escobar CR; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Wertz B; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States., Moss SJ; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Gregory MA; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Nittoli T; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.
Source: ACS omega [ACS Omega] 2025 Sep 11; Vol. 10 (37), pp. 42993-42998. Date of Electronic Publication: 2025 Sep 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41018596
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Stanley-Smith+AE%22">Stanley-Smith AE</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Coates+N%22">Coates N</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Fox+JC%22">Fox JC</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Delfino+F%22">Delfino F</searchLink>; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.<br /><searchLink fieldCode="AU" term="%22Degrado+S%22">Degrado S</searchLink>; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States.<br /><searchLink fieldCode="AU" term="%22Kunz+A%22">Kunz A</searchLink>; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.<br /><searchLink fieldCode="AU" term="%22Mao+S%22">Mao S</searchLink>; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.<br /><searchLink fieldCode="AU" term="%22Zhao+F%22">Zhao F</searchLink>; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.<br /><searchLink fieldCode="AU" term="%22Garforth+B%22">Garforth B</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Hold+A%22">Hold A</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Hong+H%22">Hong H</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Kendall+J%22">Kendall J</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Lane+J%22">Lane J</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Meï+C%22">Meï C</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Murphy+A%22">Murphy A</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Pogwizd+J%22">Pogwizd J</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Escobar+CR%22">Escobar CR</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Wertz+B%22">Wertz B</searchLink>; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States.<br /><searchLink fieldCode="AU" term="%22Moss+SJ%22">Moss SJ</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Gregory+MA%22">Gregory MA</searchLink>; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K.<br /><searchLink fieldCode="AU" term="%22Nittoli+T%22">Nittoli T</searchLink>; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101691658%22">ACS omega</searchLink> [ACS Omega] 2025 Sep 11; Vol. 10 (37), pp. 42993-42998. <i>Date of Electronic Publication: </i>2025 Sep 11 (<i>Print Publication: </i>2025).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101691658 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2470-1343 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224701343%22">24701343 </searchLink><i>NLM ISO Abbreviation: </i>ACS Omega <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41018596
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acsomega.5c05529
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 42993
    Titles:
      – TitleFull: Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Stanley-Smith AE
      – PersonEntity:
          Name:
            NameFull: Coates N
      – PersonEntity:
          Name:
            NameFull: Fox JC
      – PersonEntity:
          Name:
            NameFull: Delfino F
      – PersonEntity:
          Name:
            NameFull: Degrado S
      – PersonEntity:
          Name:
            NameFull: Kunz A
      – PersonEntity:
          Name:
            NameFull: Mao S
      – PersonEntity:
          Name:
            NameFull: Zhao F
      – PersonEntity:
          Name:
            NameFull: Garforth B
      – PersonEntity:
          Name:
            NameFull: Hold A
      – PersonEntity:
          Name:
            NameFull: Hong H
      – PersonEntity:
          Name:
            NameFull: Kendall J
      – PersonEntity:
          Name:
            NameFull: Lane J
      – PersonEntity:
          Name:
            NameFull: Meï C
      – PersonEntity:
          Name:
            NameFull: Murphy A
      – PersonEntity:
          Name:
            NameFull: Pogwizd J
      – PersonEntity:
          Name:
            NameFull: Escobar CR
      – PersonEntity:
          Name:
            NameFull: Wertz B
      – PersonEntity:
          Name:
            NameFull: Moss SJ
      – PersonEntity:
          Name:
            NameFull: Gregory MA
      – PersonEntity:
          Name:
            NameFull: Nittoli T
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 11
              M: 09
              Text: 2025 Sep 11
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2470-1343
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 37
          Titles:
            – TitleFull: ACS omega
              Type: main
ResultId 1