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Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.

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Bibliographic Details
Title: Mutasynthesis of C17- and C21-Substituted Ansamitocins for Use as ADC Payloads.
Authors: Stanley-Smith AE; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Coates N; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Fox JC; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Delfino F; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Degrado S; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States., Kunz A; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Mao S; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Zhao F; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States., Garforth B; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Hold A; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Hong H; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Kendall J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Lane J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Meï C; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Murphy A; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Pogwizd J; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Escobar CR; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Wertz B; Abzena, 360 George Patterson Blvd, Bristol, Pennsylvania 19007, United States., Moss SJ; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Gregory MA; Isomerase, Newnham Building, Chesterford Research Park, Cambridge CB10 1XL, U.K., Nittoli T; Regeneron, 777 Old Saw Mill River Road, Tarrytown, New York 10591, United States.
Source: ACS omega [ACS Omega] 2025 Sep 11; Vol. 10 (37), pp. 42993-42998. Date of Electronic Publication: 2025 Sep 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2470-1343
DOI:10.1021/acsomega.5c05529