Dexamethasone-loaded platelet-inspired nanoparticles improve intracortical microelectrode recording performance.

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Title: Dexamethasone-loaded platelet-inspired nanoparticles improve intracortical microelectrode recording performance.
Authors: Li L; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Hartzler A; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Menendez-Lustri DM; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Zhang J; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Chen A; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Lam DV; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Traylor B; Haima Therapeutics LLC, Cleveland, OH, USA., Quill E; Haima Therapeutics LLC, Cleveland, OH, USA., Nethery DE; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Hoeferlin GF; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Pawlowski CL; Haima Therapeutics LLC, Cleveland, OH, USA., Bruckman MA; Haima Therapeutics LLC, Cleveland, OH, USA., Sen Gupta A; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Capadona JR; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA., Shoffstall AJ; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA. ajs215@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH, USA. ajs215@case.edu.
Source: Nature communications [Nat Commun] 2025 Sep 29; Vol. 16 (1), pp. 8579. Date of Electronic Publication: 2025 Sep 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-63583-z