Localized delivery of Sr-doped mesoporous silica nanoparticles embedded in cryogels with adipose-derived stem cells promotes craniofacial bone regeneration in an osteoporotic rat model.

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Title: Localized delivery of Sr-doped mesoporous silica nanoparticles embedded in cryogels with adipose-derived stem cells promotes craniofacial bone regeneration in an osteoporotic rat model.
Authors: Kuo YC; Department of Plastic and Reconstructive Surgery, Keelung Chang Gung Memorial Hospital, Keelung, 204, Taiwan., Lee ZH; Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, 202, Taiwan., Tsai CH; Division of Plastic and Reconstructive Surgery, Department of Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan, 333, Taiwan., Chen CT; Division of Plastic and Reconstructive Surgery, Department of Surgery, Linkou Chang Gung Memorial Hospital, Taoyuan, 333, Taiwan., Lin HM; Department of Bioscience and Biotechnology, National Taiwan Ocean University, Keelung, 202, Taiwan. hmlin@mail.ntou.edu.tw., Chen CH; Department of Plastic and Reconstructive Surgery, Keelung Chang Gung Memorial Hospital, Keelung, 204, Taiwan. cjh5027@cgmh.org.tw.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2025 Sep 29; Vol. 16 (1), pp. 532. Date of Electronic Publication: 2025 Sep 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1757-6512
DOI:10.1186/s13287-025-04673-z