Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data.
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| Title: | Best practices and tools in R and Python for statistical processing and visualization of lipidomics and metabolomics data. |
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| Authors: | Idkowiak J; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czechia.; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI) and Leuven Institute for Single Cell Omics (LISCO), KU Leuven, Leuven, Flanders, Belgium., Dehairs J; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI) and Leuven Institute for Single Cell Omics (LISCO), KU Leuven, Leuven, Flanders, Belgium., Schwarzerová J; Department of Biomedical Engineering, Faculty of Electrical Engineering and Communication, Brno University of Technology, Brno, Czechia.; Molecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, Faculty of Life Sciences, University of Vienna, Vienna, Austria.; Department of Molecular and Clinical Pathology and Medical Genetics, University Hospital Ostrava, Ostrava, Czechia., Olešová D; Institute of Experimental Endocrinology, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia., Truong JXM; South Australian Health and Medical Research Institute (SAHMRI), North Terrace, Adelaide, SA, Australia.; South Australian immunoGENomics Cancer Institute (SAiGENCI) & Freemasons Centre for Male Health and Well-Being, The University of Adelaide Medical School, North Terrace, Adelaide, SA, Australia., Kvasnička A; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czechia.; Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway., Eftychiou M; Laboratory of Integrative Cancer Genomics, VIB-KU Leuven Center for Cancer Biology, Leuven, Flanders, Belgium.; VIB Center for AI & Computational Biology, Leuven, Flanders, Belgium.; Department of Oncology, KU Leuven, Leuven, Flanders, Belgium.; Laboratory of Multi-Omic Integrative Bioinformatics, Department of Human Genetics, KU Leuven, Leuven, Flanders, Belgium., Cools R; Laboratory of Integrative Cancer Genomics, VIB-KU Leuven Center for Cancer Biology, Leuven, Flanders, Belgium.; VIB Center for AI & Computational Biology, Leuven, Flanders, Belgium.; Department of Oncology, KU Leuven, Leuven, Flanders, Belgium., Spotbeen X; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI) and Leuven Institute for Single Cell Omics (LISCO), KU Leuven, Leuven, Flanders, Belgium., Jirásko R; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czechia., Veseli V; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czechia., Giampà M; Laboratory of Applied Mass Spectrometry, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Flanders, Belgium.; Metabolomics Core Facility, VIB-KU Leuven Center for Cancer Biology, Leuven, Flanders, Belgium., de Laat V; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI) and Leuven Institute for Single Cell Omics (LISCO), KU Leuven, Leuven, Flanders, Belgium., Butler LM; South Australian Health and Medical Research Institute (SAHMRI), North Terrace, Adelaide, SA, Australia.; South Australian immunoGENomics Cancer Institute (SAiGENCI) & Freemasons Centre for Male Health and Well-Being, The University of Adelaide Medical School, North Terrace, Adelaide, SA, Australia., Weckwerth W; Molecular Systems Biology (MOSYS), Department of Functional and Evolutionary Ecology, Faculty of Life Sciences, University of Vienna, Vienna, Austria.; Vienna Metabolomics Center (VIME), University of Vienna, Vienna, Austria., Friedecký D; Laboratory for Inherited Metabolic Disorders, Department of Clinical Biochemistry, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czechia., Demeulemeester J; Laboratory of Integrative Cancer Genomics, VIB-KU Leuven Center for Cancer Biology, Leuven, Flanders, Belgium.; VIB Center for AI & Computational Biology, Leuven, Flanders, Belgium.; Department of Oncology, KU Leuven, Leuven, Flanders, Belgium., Hron K; Department of Mathematical Analysis and Applications of Mathematics, Faculty of Science, Palacký University Olomouc, Olomouc, Czech Republic., Swinnen JV; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, Leuven Cancer Institute (LKI) and Leuven Institute for Single Cell Omics (LISCO), KU Leuven, Leuven, Flanders, Belgium., Holčapek M; Department of Analytical Chemistry, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czechia. Michal.Holcapek@upce.cz. |
| Source: | Nature communications [Nat Commun] 2025 Sep 30; Vol. 16 (1), pp. 8714. Date of Electronic Publication: 2025 Sep 30. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63751-1 |
