A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes.
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| Title: | A histone-centric multi-omics study shows that increased H3K4 methylation sustains triple-negative breast cancer phenotypes. |
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| Authors: | Noberini R; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy. roberta.noberini@ieo.it., Robusti G; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Vai A; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Savoia EO; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Jodice MG; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Bertalot G; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy.; Unità Operativa Multizonale di Anatomia Patologica, APSS, Trento, Italy.; Centre for Medical Sciences - CISMed, University of Trento, Trento, Italy., Çat B; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Pallavicini I; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy., Bonizzi G; Biobank for Translational and Digital Medicine, IEO European Institute of Oncology IRCCS, Milan, Italy., Capra M; Biobank for Translational and Digital Medicine, IEO European Institute of Oncology IRCCS, Milan, Italy., Sangalli CA; Clinical Trial Office, IEO European Institute of Oncology IRCSS, Milan, Italy., Zambelli F; Dipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy., Fusco N; Biobank for Translational and Digital Medicine, IEO European Institute of Oncology IRCCS, Milan, Italy.; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy., Pece S; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy.; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy., Pavesi G; Dipartimento di Bioscienze, Università degli Studi di Milano, Milan, Italy., Minucci S; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy.; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy., Bonaldi T; Department of Experimental Oncology, IEO European Institute of Oncology IRCSS, Milan, Italy. tiziana.bonaldi@ieo.it.; Department of Oncology and Hematology-Oncology, University of Milan, Milan, Italy. tiziana.bonaldi@ieo.it. |
| Source: | Nature communications [Nat Commun] 2025 Sep 30; Vol. 16 (1), pp. 8716. Date of Electronic Publication: 2025 Sep 30. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63745-z |
