Insights from single cell and bulk RNA sequencing: increased NOTCH signaling is correlated with oncogenic transformation of juxtaglomerular cells to juxtaglomerular cell tumors.

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Title: Insights from single cell and bulk RNA sequencing: increased NOTCH signaling is correlated with oncogenic transformation of juxtaglomerular cells to juxtaglomerular cell tumors.
Authors: Gupta S; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: gupta.sounak@mayo.edu., Dasari S; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, USA. Electronic address: Dasari.Surendra@mayo.edu., Shen W; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Shen.Wei@mayo.edu., Kipp BR; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Kipp.Benjamin@mayo.edu., Erickson LA; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: Erickson.Lori@mayo.edu., Cheville JC; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA. Electronic address: cheville.john@mayo.edu.
Source: Human pathology [Hum Pathol] 2025 Nov; Vol. 165, pp. 105939. Date of Electronic Publication: 2025 Sep 29.
Publication Type: Journal Article
Journal Info: Publisher: W B Saunders Country of Publication: United States NLM ID: 9421547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8392 (Electronic) Linking ISSN: 00468177 NLM ISO Abbreviation: Hum Pathol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-8392
DOI:10.1016/j.humpath.2025.105939