Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia.

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Title: Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia.
Authors: García-San-Martín N; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Seville, Seville, Spain.; Department of Psychology, University of Cambridge, Cambridge, UK., Bethlehem RA; Department of Psychology, University of Cambridge, Cambridge, UK., Segura P; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Seville, Seville, Spain., Mihalik A; Department of Psychiatry, University of Cambridge, Cambridge, UK., Seidlitz J; Department of Child and Adolescent Psychiatry and Behavioral Science, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Sebenius I; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK., Alemán-Morillo C; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Seville, Seville, Spain., Dorfschmidt L; Department of Child and Adolescent Psychiatry and Behavioral Science, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Shafiei G; Lifespan Brain Institute, The Children's Hospital of Philadelphia and Penn Medicine, Philadelphia, PA, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Morgan SE; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Department of Computer Science and Technology, University of Cambridge, Cambridge, UK.; School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK., Ruiz-Veguilla M; Biomedical Research Center in Mental Health Network (CIBERSAM), Health Institute Carlos III, Madrid, Spain.; Mental Health Service, Virgen del Rocío University Hospital, Seville, Spain.; Instituto de Biomedicina de Sevilla (IBiS) HUVR/CSIC, University of Seville, Seville, Spain., Ayesa-Arriola R; Biomedical Research Center in Mental Health Network (CIBERSAM), Health Institute Carlos III, Madrid, Spain.; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria, Santander, Spain., Vázquez-Bourgon J; Biomedical Research Center in Mental Health Network (CIBERSAM), Health Institute Carlos III, Madrid, Spain.; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria, Santander, Spain., Misic B; Montreal Neurological Institute, McGill University, Montreal, QC, Canada., Suckling J; Department of Psychiatry, University of Cambridge, Cambridge, UK.; Peterborough NHS Foundation Trust, Peterborough, UK., Crespo-Facorro B; Biomedical Research Center in Mental Health Network (CIBERSAM), Health Institute Carlos III, Madrid, Spain.; Mental Health Service, Virgen del Rocío University Hospital, Seville, Spain.; Instituto de Biomedicina de Sevilla (IBiS) HUVR/CSIC, University of Seville, Seville, Spain.; Department of Psychiatry, Marqués de Valdecilla University Hospital, IDIVAL, School of Medicine, University of Cantabria, Santander, Spain., Romero-García R; Department of Medical Physiology and Biophysics, Faculty of Medicine, University of Seville, Seville, Spain. rromerog@us.es.; Department of Psychiatry, University of Cambridge, Cambridge, UK. rromerog@us.es.; Biomedical Research Center in Mental Health Network (CIBERSAM), Health Institute Carlos III, Madrid, Spain. rromerog@us.es.; Instituto de Biomedicina de Sevilla (IBiS) HUVR/CSIC, University of Seville, Seville, Spain. rromerog@us.es.
Source: Nature communications [Nat Commun] 2025 Oct 01; Vol. 16 (1), pp. 8745. Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-63792-6