Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease.

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Title: Molecular hallmarks of excitatory and inhibitory neuronal resilience to Alzheimer's disease.
Authors: Castanho I; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Naderi Yeganeh P; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Boix CA; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Morgan SL; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Centre for Neuroscience, Surgery and Trauma, Blizard Institute, Queen Mary University of London, London, UK., Mathys H; University of Pittsburgh Brain Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA., Prokopenko D; Harvard Medical School, Boston, MA, USA.; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA., White B; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Soto LM; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Pegoraro G; Harvard Medical School, Boston, MA, USA.; Medical School, University of Exeter, Exeter, UK., Shah S; Harvard Medical School, Boston, MA, USA., Ploumakis A; Harvard Medical School, Boston, MA, USA.; Spatial Technologies Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA., Kalavros N; Harvard Medical School, Boston, MA, USA.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Spatial Technologies Unit, Beth Israel Deaconess Medical Center, Boston, MA, USA., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Lange C; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Kim DY; Harvard Medical School, Boston, MA, USA.; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA.; McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA.; Genetics and Aging Research Unit, The Henry and Allison McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA., Bertram L; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Cardiogenetics, University of Lübeck, Lübeck, Germany.; Department of Psychology, University of Oslo, Oslo, Norway., Tsai LH; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Picower Institute for Learning and Memory, MIT, Cambridge, MA, USA.; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA, USA., Kellis M; Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Tanzi RE; Harvard Medical School, Boston, MA, USA. rtanzi@mgh.harvard.edu.; Genetics and Aging Research Unit, MassGeneral Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, USA. rtanzi@mgh.harvard.edu.; McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA. rtanzi@mgh.harvard.edu.; Genetics and Aging Research Unit, The Henry and Allison McCance Center for Brain Health, Department of Neurology, Massachusetts General Hospital, Boston, MA, USA. rtanzi@mgh.harvard.edu., Hide W; Harvard Medical School, Boston, MA, USA. whide@bidmc.harvard.edu.; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA, USA. whide@bidmc.harvard.edu.
Source: Molecular neurodegeneration [Mol Neurodegener] 2025 Oct 01; Vol. 20 (1), pp. 103. Date of Electronic Publication: 2025 Oct 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1750-1326
DOI:10.1186/s13024-025-00892-3