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Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.

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Bibliographic Details
Title: Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.
Authors: Duggan WP; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Azimi M; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Flanagan L; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sullivan GP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Reynolds IS; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Fay J; RCSI Biobank Service, Beaumont Hospital, Dublin, Ireland., Dussmann H; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Ní Chonghaile T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sheehan KM; Department of Pathology, Royal College of Surgeons in Ireland, Dublin, Ireland., Jirström K; Department of Clinical Sciences Lund, Oncology and Therapeutic Pathology, Lund University, Lund, Sweden., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Burke JP; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland. johnburke@rcsi.com.
Source: The pharmacogenomics journal [Pharmacogenomics J] 2025 Oct 03; Vol. 25 (5), pp. 26. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101083949 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-1150 (Electronic) Linking ISSN: 1470269X NLM ISO Abbreviation: Pharmacogenomics J Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1473-1150
DOI:10.1038/s41397-025-00384-z