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Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.

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Title: Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.
Authors: Duggan WP; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Azimi M; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Flanagan L; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sullivan GP; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Reynolds IS; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Fay J; RCSI Biobank Service, Beaumont Hospital, Dublin, Ireland., Dussmann H; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Ní Chonghaile T; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Sheehan KM; Department of Pathology, Royal College of Surgeons in Ireland, Dublin, Ireland., Jirström K; Department of Clinical Sciences Lund, Oncology and Therapeutic Pathology, Lund University, Lund, Sweden., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland., Burke JP; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland. johnburke@rcsi.com.
Source: The pharmacogenomics journal [Pharmacogenomics J] 2025 Oct 03; Vol. 25 (5), pp. 26. Date of Electronic Publication: 2025 Oct 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101083949 Publication Model: Electronic Cited Medium: Internet ISSN: 1473-1150 (Electronic) Linking ISSN: 1470269X NLM ISO Abbreviation: Pharmacogenomics J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Serine-arginine protein kinase 1 (SRPK1) is under-expressed in mucinous colorectal cancer, and may mediate resistance to oxaliplatin.
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  Data: <searchLink fieldCode="AU" term="%22Duggan+WP%22">Duggan WP</searchLink>; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Azimi+M%22">Azimi M</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Flanagan+L%22">Flanagan L</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Sullivan+GP%22">Sullivan GP</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Reynolds+IS%22">Reynolds IS</searchLink>; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Fay+J%22">Fay J</searchLink>; RCSI Biobank Service, Beaumont Hospital, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Dussmann+H%22">Dussmann H</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Ní+Chonghaile+T%22">Ní Chonghaile T</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Sheehan+KM%22">Sheehan KM</searchLink>; Department of Pathology, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Jirström+K%22">Jirström K</searchLink>; Department of Clinical Sciences Lund, Oncology and Therapeutic Pathology, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Prehn+JHM%22">Prehn JHM</searchLink>; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Burke+JP%22">Burke JP</searchLink>; Department of Colorectal Surgery, Beaumont Hospital, Dublin, Ireland. johnburke@rcsi.com.
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  Data: <searchLink fieldCode="JN" term="%22101083949%22">The pharmacogenomics journal</searchLink> [Pharmacogenomics J] 2025 Oct 03; Vol. 25 (5), pp. 26. <i>Date of Electronic Publication: </i>2025 Oct 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101083949 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1473-1150 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221470269X%22">1470269X </searchLink><i>NLM ISO Abbreviation: </i>Pharmacogenomics J <i>Subsets: </i>MEDLINE
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