Treating and triggering hyperinflammation: tackling hemophagocytic lymphohistiocytosis and HLH-like syndromes in the pediatric cell therapy and critical care setting.

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Title: Treating and triggering hyperinflammation: tackling hemophagocytic lymphohistiocytosis and HLH-like syndromes in the pediatric cell therapy and critical care setting.
Authors: Wobma H; Harvard Medical School, Boston, MA, United States.; Division of Immunology, Boston Children's Hospital, Boston, MA, United States., Henderson LA; Harvard Medical School, Boston, MA, United States.; Division of Immunology, Boston Children's Hospital, Boston, MA, United States., Duncan CN; Harvard Medical School, Boston, MA, United States.; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, United States., Prockop SE; Harvard Medical School, Boston, MA, United States.; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, United States., Randolph AG; Harvard Medical School, Boston, MA, United States.; Division of Critical Care, Boston Children's Hospital, Boston, MA, United States., Degar BA; Harvard Medical School, Boston, MA, United States.; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, United States., Lehmann LE; Harvard Medical School, Boston, MA, United States.; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, United States., Baumeister SHC; Harvard Medical School, Boston, MA, United States.; Division of Hematology-Oncology, Boston Children's Hospital, Boston, MA, United States.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, United States.
Source: Frontiers in oncology [Front Oncol] 2025 Sep 19; Vol. 15, pp. 1631557. Date of Electronic Publication: 2025 Sep 19 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2234-943X
DOI:10.3389/fonc.2025.1631557