Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspective.

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Title: Key considerations for advancing chimeric antigen receptor (CAR) T-cell therapy for systemic lupus erythematosus (SLE): a multi-partner/disciplinary working group perspective.
Authors: Hsieh EWY; Department of Immunology and Microbiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA lupusabc@lupusresearch.org., Chung JB; Amgen Inc, Thousand Oaks, California, USA., Amin A; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Askanase AD; Columbia University Irving Medical Center, New York, New York, USA., Bartok B; Gilead Sciences Inc, Foster City, California, USA., Brunetta P; Sana Biotechnology Inc, Seattle, Washington, USA., Carrasco-Alfonso MJ; AstraZeneca, Boston, Massachusetts, USA., Coney C; Lupus Voices Council, Lupus Research Alliance, New York, New York, USA., Cooper JC; Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA., Dall'Era M; University of California San Francisco, San Francisco, California, USA., Delev N; Bristol Myers Squibb Co, Princeton, New Jersey, USA., Eldred A; AbbVie Inc, North Chicago, Illinois, USA., Furie RA; Division of Rheumatology, Northwell Health, Great Neck, New York, USA., Garces S; Bristol Myers Squibb Co, Princeton, New Jersey, USA., Groover K; Michigan Lupus Foundation, Traverse City, Michigan, USA., Harrington M; Fluent in Science, LLC, New York, New York, USA., Hogan JJ; Cabaletta Bio Inc, Philadelphia, Pennsylvania, USA., Imperato GH; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Jackson M; Lupus Research Alliance, New York, New York, USA., Jackson SW; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Washington, USA., Jongco AM; GlaxoSmithKline, Philadelphia, Pennsylvania, USA., Karis E; Nkarta Inc, South San Francisco, California, USA., Koegel A; Bristol Myers Squibb Co, Princeton, New Jersey, USA., König MF; Division of Rheumatology, Department of Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Ludwig Center, Johns Hopkins Medicine Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA., Koretzky G; Cornell University, Ithaca, New York, USA., Kumar V; Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, Maryland, USA., Morand E; School of Clinical Sciences, Monash University, Clayton, Victoria, Australia.; Monash Health, Clayton, Victoria, Australia., Payne AS; Columbia University Irving Medical Center, New York, New York, USA., Popat V; Center for Biologics Research and Evaluation, US Food and Drug Administration, Silver Spring, Maryland, USA., Rizvi N; Synthekine Inc, Menlo Park, California, USA., Rohan P; Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, Maryland, USA., Sadelain M; Columbia University Irving Medical Center, New York, New York, USA., Schett G; Department of Medicine 3-Rheumatology and Immunology and Deutshes Zentrum Immuntherapie, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Erlangen, BY, Germany.; Universitatsklinikum Erlangen, Erlangen, BY, Germany., Singh AP; Takeda Pharmaceuticals America Inc, Cambridge, Massachusetts, USA., van Vollenhoven RF; Department of Rheumatology, Amsterdam University Medical Center, Amsterdam, Netherlands., Zack D; Fate Therapeutics Inc, San Diego, California, USA.
Corporate Authors: Lupus ABC CAR T Working Group
Source: RMD open [RMD Open] 2025 Oct 05; Vol. 11 (4). Date of Electronic Publication: 2025 Oct 05.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: BMJ Publishing Group Country of Publication: England NLM ID: 101662038 Publication Model: Electronic Cited Medium: Internet ISSN: 2056-5933 (Electronic) Linking ISSN: 20565933 NLM ISO Abbreviation: RMD Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2056-5933
DOI:10.1136/rmdopen-2025-005866