HIF1 activity in photoreceptors drives type 3 neovascularization and retinal atrophy in a new mouse model of age-related macular degeneration.
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| Title: | HIF1 activity in photoreceptors drives type 3 neovascularization and retinal atrophy in a new mouse model of age-related macular degeneration. |
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| Authors: | Geiger F; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Heigl T; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Merolla L; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Yong M; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland.; Neuroscience Center, University of Zürich, Zürich, Switzerland., Wögenstein GM; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland.; Neuroscience Center, University of Zürich, Zürich, Switzerland., Govers LP; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Tsioti I; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Fottner A; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Samardzija M; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland., Grimm C; Lab for Retinal Cell Biology, Dept. Ophthalmology, University of Zürich, Zürich, Switzerland. cgrimm@opht.uzh.ch.; Neuroscience Center, University of Zürich, Zürich, Switzerland. cgrimm@opht.uzh.ch. |
| Source: | Cell death & disease [Cell Death Dis] 2025 Oct 06; Vol. 16 (1), pp. 687. Date of Electronic Publication: 2025 Oct 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-4889 |
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| DOI: | 10.1038/s41419-025-08028-7 |