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Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult.

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Title: Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult.
Authors: Sibale LL; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi. lsibale@mlw.mw.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK. lsibale@mlw.mw.; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. lsibale@mlw.mw., Lo SW; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Milner Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK.; The Great Ormond Street Institute of Child Health, University College London, London, UK., Kalata N; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi., Nyazika TK; Department of Biomedical Sciences and Physiology, School of Life Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK., Mitole N; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi., Dyster V; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Kusakala A; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi., Khwiya M; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi., Sagawa G; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi., Phiri JA; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK., Kalizang'oma A; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Swarthout TD; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Malisita K; Lighthouse-Queen Elizabeth Hospital and Gateway Health Centre, Blantyre, Malawi., Kamng'ona AW; School of Life Science and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi., Heyderman RS; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Bentley SD; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Kwambana-Adams BA; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK., Chaguza C; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT, USA.; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA., Jambo KC; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi. kondwani.jambo@lstmed.ac.uk.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK. kondwani.jambo@lstmed.ac.uk.; School of Life Science and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi. kondwani.jambo@lstmed.ac.uk.
Source: Nature communications [Nat Commun] 2025 Oct 07; Vol. 16 (1), pp. 8920. Date of Electronic Publication: 2025 Oct 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Within-host genetic diversity of pneumococcal serotype 3 during one-year prolonged carriage in a healthy adult.
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  Data: <searchLink fieldCode="AU" term="%22Sibale+LL%22">Sibale LL</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi. lsibale@mlw.mw.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK. lsibale@mlw.mw.; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. lsibale@mlw.mw.<br /><searchLink fieldCode="AU" term="%22Lo+SW%22">Lo SW</searchLink>; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Milner Centre for Evolution, Department of Life Sciences, University of Bath, Bath, UK.; The Great Ormond Street Institute of Child Health, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kalata+N%22">Kalata N</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Nyazika+TK%22">Nyazika TK</searchLink>; Department of Biomedical Sciences and Physiology, School of Life Sciences, Faculty of Science and Engineering, University of Wolverhampton, Wolverhampton, UK.<br /><searchLink fieldCode="AU" term="%22Mitole+N%22">Mitole N</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Dyster+V%22">Dyster V</searchLink>; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kusakala+A%22">Kusakala A</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Khwiya+M%22">Khwiya M</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Sagawa+G%22">Sagawa G</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Phiri+JA%22">Phiri JA</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Kalizang'oma+A%22">Kalizang'oma A</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Swarthout+TD%22">Swarthout TD</searchLink>; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Malisita+K%22">Malisita K</searchLink>; Lighthouse-Queen Elizabeth Hospital and Gateway Health Centre, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Kamng'ona+AW%22">Kamng'ona AW</searchLink>; School of Life Science and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi.<br /><searchLink fieldCode="AU" term="%22Heyderman+RS%22">Heyderman RS</searchLink>; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Bentley+SD%22">Bentley SD</searchLink>; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Kwambana-Adams+BA%22">Kwambana-Adams BA</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chaguza+C%22">Chaguza C</searchLink>; Parasites and Microbes, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Research Department of Infection, Division of Infection and Immunity, University College London, London, UK.; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, CT, USA.; Department of Host-Microbe Interactions, St. Jude Children's Research Hospital, Memphis, TN, USA.<br /><searchLink fieldCode="AU" term="%22Jambo+KC%22">Jambo KC</searchLink>; Malawi-Liverpool-Wellcome Programme, Blantyre, Malawi. kondwani.jambo@lstmed.ac.uk.; Department of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK. kondwani.jambo@lstmed.ac.uk.; School of Life Science and Allied Health Professions, Kamuzu University of Health Sciences, Blantyre, Malawi. kondwani.jambo@lstmed.ac.uk.
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