Decoding BRCA1 promoter hypermethylation: a new frontier in understanding sporadic breast cancer.

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Title: Decoding BRCA1 promoter hypermethylation: a new frontier in understanding sporadic breast cancer.
Authors: Patra D; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Department of Immunology, UPMC Hilman Cancer Centre, University of Pittsburgh, Pittsburgh, PA, USA., Varghese GR; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Department of General Virology, Institute of Advanced Virology, Thiruvananthapuram, Kerala, India., Jaikumar VS; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; University of South Australia, Adelaide, SA, Australia., Rajan A; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Department of General Virology, Institute of Advanced Virology, Thiruvananthapuram, Kerala, India., Krishnan N; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India., Kuppuswamy K; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Bioscience Research and Training Centre, Thonnakkal, Thiruvananthapuram, Kerala, India., Thankappan R; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India.; Department of Molecular Biology and Genetics, DDRC Agilus Diagnostics, Ernakulam, Kerala, India., Srinivas P; Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India. priyasrinivas@rgcb.res.in.
Source: Cancer gene therapy [Cancer Gene Ther] 2025 Dec; Vol. 32 (12), pp. 1400-1413. Date of Electronic Publication: 2025 Oct 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9432230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5500 (Electronic) Linking ISSN: 09291903 NLM ISO Abbreviation: Cancer Gene Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5500
DOI:10.1038/s41417-025-00969-7