Podocyte-directed VEGFC gene therapy prevents increased glomerular permeability and glycocalyx damage in experimental type 1 diabetes.

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Title: Podocyte-directed VEGFC gene therapy prevents increased glomerular permeability and glycocalyx damage in experimental type 1 diabetes.
Authors: Martin Alonso A; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., May CJ; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Stowell-Connolly H; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Wu H; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Gamez M; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Ourradi K; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Ramnath RD; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Ding WY; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Welsh GI; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Satchell SC; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK., Foster RR; Bristol Renal, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol BS1 3NY, UK. Electronic address: becky.foster@bristol.ac.uk.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2026 Jan 07; Vol. 34 (1), pp. 117-122. Date of Electronic Publication: 2025 Oct 06.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1525-0024
DOI:10.1016/j.ymthe.2025.10.001