Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling.
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| Title: | Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling. |
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| Authors: | Hwang JS; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Kang J; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Kim J; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Eun K; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., West S; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA., Bacho HE; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Avalos V; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Shuff S; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Shin DM; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Saba NF; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Magliocca KR; Department of Pathology & Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA., Qu CK; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA., Fu H; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA.; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA., Ramalingam SS; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA., Ivanov AA; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA., Hitosugi T; Department of Oncology, Division of Oncology Research, Mayo Clinic, Rochester, MN, USA., Kang S; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory, Emory University School of Medicine, Atlanta, GA, USA. smkang@emory.edu. |
| Source: | Nature communications [Nat Commun] 2025 Oct 08; Vol. 16 (1), pp. 8932. Date of Electronic Publication: 2025 Oct 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-63892-3 |
