Propofol in combination with salvianolic acid A protect against lipopolysaccharide-induced cardiac dysfunction and ferroptosis through activating the SIRT1/FoxO1 signaling under diabetic condition.

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Title: Propofol in combination with salvianolic acid A protect against lipopolysaccharide-induced cardiac dysfunction and ferroptosis through activating the SIRT1/FoxO1 signaling under diabetic condition.
Authors: Han R; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.; Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.; State Key Laboratory of Quality Research in Chinese Medicine, Faculty of Chinese Medicine, Macau University of Science and Technology, Macao, China., Han K; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Zhu J; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Zhang A; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Zhou J; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Huang H; Department of Emergency, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Han H; Department of Anesthesiology, The Eighth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China., Zhang L; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Liu X; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Tang J; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Yi B; Department of Anesthesiology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China., Ma X; Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China., Chu Q; Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China., Mo G; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China., Shao Y; Department of Intensive Care Unit, The First Dongguan Affiliated Hospital, Guangdong Medical University, Zhanjiang, China.; Department of Key Laboratory of Sepsis Translational Medicine, Guangdong Medical University, Zhanjiang, China., Xia Z; Department of Anesthesiology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.; Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.; State Key Laboratory of Pharmaceutical Biotechnology, Department of Medicine, The University of Hong Kong, Hong Kong, China.
Source: Annals of medicine [Ann Med] 2025 Dec; Vol. 57 (1), pp. 2570796. Date of Electronic Publication: 2025 Oct 09.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 8906388 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2060 (Electronic) Linking ISSN: 07853890 NLM ISO Abbreviation: Ann Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1365-2060
DOI:10.1080/07853890.2025.2570796