PLAN-psoriasis: protocol for a randomised controlled feasibility trial comparing patient-led 'as-needed' treatment and therapeutic drug monitoring-guided treatment to continuous treatment for adults with clear or almost clear skin on risankizumab monotherapy for psoriasis.

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Title: PLAN-psoriasis: protocol for a randomised controlled feasibility trial comparing patient-led 'as-needed' treatment and therapeutic drug monitoring-guided treatment to continuous treatment for adults with clear or almost clear skin on risankizumab monotherapy for psoriasis.
Authors: Ye W; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Powell K; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Dooley N; Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK., Thomas CM; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Coker B; Research and Development, Guy's and St Thomas' NHS Foundation Trust, London, UK., McAteer H; Psoriasis Association, Northampton, UK., Wei JR; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Tan WR; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Baudry D; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Dasandi T; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Pizzato J; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Sach TH; School of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, UK., Gregory J; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Yang Z; Centre for Rheumatic Diseases, King's College London, London, UK., Pink AE; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Woolf RT; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Warren RB; Dermatology Centre, Northern Care Alliance NHS Foundation Trust & Division of Musculoskeletal and Dermatological Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK., Weinman J; Centre for Adherence Research and Education, King's College London, London, UK., Barker JN; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., Chapman S; Centre for Adherence Research and Education, King's College London, London, UK., Standing JF; Infection, Immunity and Inflammation Research & Teaching Department, UCL Great Ormond Street Institute of Child Health, London, UK., Norton S; Centre for Rheumatic Diseases, King's College London, London, UK., Smith CH; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK., K Mahil S; St John's Institute of Dermatology, Guy's and St Thomas' NHS Foundation Trust & King's College London, London, UK satveer.mahil@kcl.ac.uk.
Source: BMJ open [BMJ Open] 2025 Oct 10; Vol. 15 (10), pp. e106635. Date of Electronic Publication: 2025 Oct 10.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-106635