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A novel scalable method for the production of rennet-treated milk-derived extracellular vesicles for improved curcumin oral delivery.

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Title: A novel scalable method for the production of rennet-treated milk-derived extracellular vesicles for improved curcumin oral delivery.
Authors: Schifano E; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy., Vari F; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, Rome, Italy., Buccini L; Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Rome, Italy.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy., Karimova M; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy., Syman K; Department of Biology Faculty of Natural Science and Geography, Abai KazakhNational Pedagogical University Almaty, Almaty, Kazakhstan., Varnadyan D; Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy., Uccelletti D; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy., Dinarelli S; Institute for the Structure of Matter, National Research Council, Roma, Italy., Zuccotti M; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia, Italy., Alfieri A; Centro Grandi Strumenti, University of Pavia, Pavia, Italy., Sennato S; Institute for Complex Systems (ISC)-CNR and Physics Department, Sapienza University, Rome, Italy., Mura F; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy., Rossi M; Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Rome, Italy.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy., Dini L; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy. luciana.dini@uniroma1.it.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy. luciana.dini@uniroma1.it., Tacconi S; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy. stefano.tacconi@uniroma1.it.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy. stefano.tacconi@uniroma1.it.
Source: Journal of nanobiotechnology [J Nanobiotechnology] 2025 Oct 10; Vol. 23 (1), pp. 656. Date of Electronic Publication: 2025 Oct 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel scalable method for the production of rennet-treated milk-derived extracellular vesicles for improved curcumin oral delivery.
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  Data: <searchLink fieldCode="AU" term="%22Schifano+E%22">Schifano E</searchLink>; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Vari+F%22">Vari F</searchLink>; Department of Physiology and Pharmacology 'V. Erspamer', Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Buccini+L%22">Buccini L</searchLink>; Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Rome, Italy.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Karimova+M%22">Karimova M</searchLink>; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Syman+K%22">Syman K</searchLink>; Department of Biology Faculty of Natural Science and Geography, Abai KazakhNational Pedagogical University Almaty, Almaty, Kazakhstan.<br /><searchLink fieldCode="AU" term="%22Varnadyan+D%22">Varnadyan D</searchLink>; Department of Biological and Environmental Sciences and Technologies (Di.S.Te.B.A.), University of Salento, Lecce, Italy.<br /><searchLink fieldCode="AU" term="%22Uccelletti+D%22">Uccelletti D</searchLink>; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Dinarelli+S%22">Dinarelli S</searchLink>; Institute for the Structure of Matter, National Research Council, Roma, Italy.<br /><searchLink fieldCode="AU" term="%22Zuccotti+M%22">Zuccotti M</searchLink>; Department of Biology and Biotechnology 'Lazzaro Spallanzani', University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Alfieri+A%22">Alfieri A</searchLink>; Centro Grandi Strumenti, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Sennato+S%22">Sennato S</searchLink>; Institute for Complex Systems (ISC)-CNR and Physics Department, Sapienza University, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Mura+F%22">Mura F</searchLink>; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+M%22">Rossi M</searchLink>; Department of Basic and Applied Sciences for Engineering, Sapienza University of Rome, Rome, Italy.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Dini+L%22">Dini L</searchLink>; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy. luciana.dini@uniroma1.it.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy. luciana.dini@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Tacconi+S%22">Tacconi S</searchLink>; Department of Biology and Biotechnologies 'C. Darwin', Sapienza University of Rome, Rome, Italy. stefano.tacconi@uniroma1.it.; Research Center of Nanotechnologies for Engineering (CNIS), Sapienza University of Rome, Rome, Italy. stefano.tacconi@uniroma1.it.
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  Data: <searchLink fieldCode="JN" term="%22101152208%22">Journal of nanobiotechnology</searchLink> [J Nanobiotechnology] 2025 Oct 10; Vol. 23 (1), pp. 656. <i>Date of Electronic Publication: </i>2025 Oct 10.
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              Text: 2025 Oct 10
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