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Myeloid ADAM17 induces ST2+ T regulatory cells that limit obesity-induced metabolic inflammation through changes in both membrane and soluble TNF.

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Title: Myeloid ADAM17 induces ST2+ T regulatory cells that limit obesity-induced metabolic inflammation through changes in both membrane and soluble TNF.
Authors: Lownik JC; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States; Center for Clinical and Translational Research, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Zellner MP; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Farrar J; Center for Clinical and Translational Research, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Tharakan A; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Celi FS; Division of Endocrinology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Conrad DH; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States., Martin RK; Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States. Electronic address: Rebecca.Martin@vcuhealth.org.
Source: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2025 Nov; Vol. 192, pp. 118627. Date of Electronic Publication: 2025 Oct 10.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1950-6007
DOI:10.1016/j.biopha.2025.118627