Diabetes-induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice.

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Title: Diabetes-induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice.
Authors: Fülöp K; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Kozák E; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Tőkési N; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Kocsis L; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Kelemen A; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Geszti Z; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Kutás A; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Harangi M; Division of Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.; Vascular Pathophysiology Research Group 11003, University of Debrecen, HUN-REN, Debrecen, Hungary., Diószegi Á; Division of Metabolism, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Rapi Z; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary., Balla J; Vascular Pathophysiology Research Group 11003, University of Debrecen, HUN-REN, Debrecen, Hungary.; Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary., Le Saux O; Department of Cell and Molecular Biology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA., Váradi A; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary., Pomozi V; Institute of Molecular Life Sciences, Research Centre for Natural Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN, Budapest, Hungary.
Source: FEBS open bio [FEBS Open Bio] 2026 Mar; Vol. 16 (3), pp. 474-486. Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: England NLM ID: 101580716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-5463 (Electronic) Linking ISSN: 22115463 NLM ISO Abbreviation: FEBS Open Bio Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2211-5463
DOI:10.1002/2211-5463.70141