Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerization.
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| Title: | Apomorphine is a novel necroptosis inhibitor targeting mixed lineage kinase domain-like protein oligomerization. |
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| Authors: | Han M; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea., Seo DH; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea., Kwak MS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Park IH; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea., Rhee WJ; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Kim HS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Jeon E; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Lee JJ; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea., Park CH; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea., Kim ND; Voronoibio Inc., Yeonsu-gu, South Korea., Sim T; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea.; Department of Biomedical Sciences, Yonsei University College of Medicine, Seoul, South Korea., Kim YS; Department of Biochemistry, Ajou University School of Medicine, Yeongtong-gu, Republic of Korea.; Department of Biomedical Sciences, Graduate School of Ajou University, Yeongtong-gu, Republic of Korea., Ryu KS; Ochang Center, Korea Basic Science Institute, Cheongju-Si, South Korea. ksryu@kbsi.re.kr.; KBSI School of Bioscience, University of Science and Technology, Daejeon, South Korea. ksryu@kbsi.re.kr., Shin JS; Department of Microbiology, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Brain Korea 21 FOUR Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, South Korea. jsshin6203@yuhs.ac.; Center for Nanomedicine, Institute for Basic Science (IBS), Yonsei University, Seoul, South Korea. jsshin6203@yuhs.ac. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Oct 13; Vol. 11 (1), pp. 457. Date of Electronic Publication: 2025 Oct 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2058-7716 |
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| DOI: | 10.1038/s41420-025-02763-8 |
