Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes.
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| Title: | Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes. |
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| Authors: | Rylaarsdam LE; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. rylaarsd@ohsu.edu., Skubi BW; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA., Nichols RV; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA., O'Connell BL; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA., Kotnik JH; M.D./Ph.D. Training Program, Oregon Health & Science University, Portland, OR, USA., Coleman SD; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Yardımcı GG; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Adey AC; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu. |
| Source: | Communications biology [Commun Biol] 2025 Oct 14; Vol. 8 (1), pp. 1468. Date of Electronic Publication: 2025 Oct 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-025-08859-2 |