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Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes.

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Title: Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes.
Authors: Rylaarsdam LE; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. rylaarsd@ohsu.edu., Skubi BW; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA., Nichols RV; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA., O'Connell BL; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA., Kotnik JH; M.D./Ph.D. Training Program, Oregon Health & Science University, Portland, OR, USA., Coleman SD; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Yardımcı GG; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA., Adey AC; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.
Source: Communications biology [Commun Biol] 2025 Oct 14; Vol. 8 (1), pp. 1468. Date of Electronic Publication: 2025 Oct 14.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell DNA methylation analysis tool Amethyst resolves distinct non-CG methylation patterns in human astrocytes and oligodendrocytes.
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  Data: <searchLink fieldCode="AU" term="%22Rylaarsdam+LE%22">Rylaarsdam LE</searchLink>; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. rylaarsd@ohsu.edu.<br /><searchLink fieldCode="AU" term="%22Skubi+BW%22">Skubi BW</searchLink>; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Nichols+RV%22">Nichols RV</searchLink>; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22O'Connell+BL%22">O'Connell BL</searchLink>; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Kotnik+JH%22">Kotnik JH</searchLink>; M.D./Ph.D. Training Program, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Coleman+SD%22">Coleman SD</searchLink>; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Yardımcı+GG%22">Yardımcı GG</searchLink>; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA.; Division of Oncological Sciences, Oregon Health & Science University, Portland, OR, USA.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA.<br /><searchLink fieldCode="AU" term="%22Adey+AC%22">Adey AC</searchLink>; Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Cancer Early Detection Advanced Research Center, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cancer Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.; Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, USA. adey@ohsu.edu.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2025 Oct 14; Vol. 8 (1), pp. 1468. <i>Date of Electronic Publication: </i>2025 Oct 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+UK%22">Nature Publishing Group UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101719179 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2399-3642 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223993642%22">23993642 </searchLink><i>NLM ISO Abbreviation: </i>Commun Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s42003-025-08859-2
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              Text: 2025 Oct 14
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